Department of Anesthesiology, University of Wisconsin Hospitals & Clinics, 600 Highland Ave., Madison, WI 53792, USA.
Department of Anesthesiology, Ohio State University Wexner Medical Center, 370 W. 9th Ave., Columbus, OH 43210, USA.
Medicina (Kaunas). 2022 Dec 9;58(12):1815. doi: 10.3390/medicina58121815.
The rates of survival with functional recovery for out of hospital cardiac arrest remain unacceptably low. Extracorporeal cardiopulmonary resuscitation (ECPR) quickly resolves the low-flow state of conventional cardiopulmonary resuscitation (CCPR) providing valuable perfusion to end organs. Observational studies have shown an association with the use of ECPR and improved survivability. Two recent randomized controlled studies have demonstrated improved survival with functional neurologic recovery when compared to CCPR. Substantial resources and coordination amongst different specialties and departments are crucial for the successful implementation of ECPR. Standardized protocols, simulation based training, and constant communication are invaluable to the sustainability of a program. Currently there is no standardized protocol for the post-cannulation management of these ECPR patients and, ideally, upcoming studies should aim to evaluate these protocols.
院外心脏骤停患者的生存率和功能恢复率仍然低得令人无法接受。体外心肺复苏（ECPR）可迅速解决常规心肺复苏（CCPR）的低血流状态，为终末器官提供有价值的灌注。观察性研究表明，ECPR 的使用与存活率的提高有关。两项最近的随机对照研究表明，与 CCPR 相比，ECPR 可提高生存和功能神经恢复的几率。不同专业和科室之间的大量资源和协调对于 ECPR 的成功实施至关重要。标准化方案、基于模拟的培训和持续沟通对于计划的可持续性是非常宝贵的。目前，对于这些 ECPR 患者的插管后管理尚无标准化方案，理想情况下，未来的研究应旨在评估这些方案。
