Department of Veterinary Sciences, University of Pisa, Viale delle Piagge 2, 56124 Pisa, Italy.
Centro Interdipartimentale di Ricerca "Nutraceutica e Alimentazione per la Salute", University of Pisa, Via del Borghetto 80, 56124 Pisa, Italy.
Molecules. 2022 Dec 19;27(24):9067. doi: 10.3390/molecules27249067.
Herbal remedia are widely employed in folk medicine, and have been more and more often studied and considered in the treatment of several infections. Sarcoptic mange (scabies, when referring to human patients) is a highly contagious skin disease caused by (sarcoptiformes, Sarcoptinae), an astigmatid mite which burrows into the epidermis, actively penetrating the This parasitosis negatively affects livestock productions and represents a constraint on animal and human health. The treatment relies on permethrine and ivermectine but, since these molecules do not have ovicidal action, more than a single dose should be administered. Toxicity, the possible onset of parasite resistance, the presence of residues in meat and other animal products and environmental contamination are the major constraints. These shortcomings could be reduced by the use of plant extracts that have been in vitro or in vivo checked against these mites, sometimes with promising results. The aim of the present study was to review the literature dealing with the treatment of both scabies and sarcoptic mange by plant-derived agents, notably essential oils.
草药疗法在民间医学中被广泛应用,并且在治疗多种感染方面的研究和应用也越来越多。疥螨病(当涉及人类患者时称为疥疮)是一种高度传染性的皮肤病,由(疥螨目,疥螨科)的一种变形螨引起,这种螨钻入表皮,积极穿透表皮。这种寄生虫病对畜牧业生产有负面影响,也是动物和人类健康的一个制约因素。治疗方法依赖于扑灭司林和伊维菌素,但由于这些分子没有杀卵作用,应该给予不止一剂。毒性、寄生虫可能产生抗药性、肉和其他动物产品中存在残留物以及环境污染是主要的限制因素。通过使用已在体外或体内针对这些螨虫进行过检查的植物提取物可以减少这些缺点,有时效果令人鼓舞。本研究的目的是综述有关植物衍生制剂(特别是精油)治疗疥疮和疥螨病的文献。