Portenoy R K, Lipton R B, Berger A R, Lesser M L, Lantos G
Department of Neurology, Albert Einstein College of Medicine, New York, Bronx 10461.
J Neurol Neurosurg Psychiatry. 1987 Aug;50(8):976-9. doi: 10.1136/jnnp.50.8.976.
The hospital charts and CT scans of 112 patients with spontaneous supratentorial haemorrhage were retrospectively reviewed to evaluate factors important to prognosis. A low Glasgow Coma Scale score, coma, ataxic respiration, abnormal pupils, acute hypertension, large haemorrhage size and intraventricular extension of blood were associated with a poor outcome. Multivariate analysis using the technique of logistic regression identified three variables, the Glasgow Coma Scale score, haemorrhage size and intraventricular extension of blood, which were most predictive of outcome. A model was developed from this analysis which accurately estimates the probability of good outcome and the risk of poor outcome based on data available on presentation. With additional validation, this model may be useful in choosing patients for surgical evacuation of haematomas.
回顾性分析112例自发性幕上脑出血患者的医院病历和CT扫描,以评估对预后重要的因素。格拉斯哥昏迷量表评分低、昏迷、共济失调呼吸、瞳孔异常、急性高血压、出血量大和血液脑室扩展与预后不良相关。使用逻辑回归技术进行多变量分析确定了三个变量,即格拉斯哥昏迷量表评分、出血大小和血液脑室扩展,这三个变量对预后的预测性最强。基于该分析建立了一个模型,该模型可根据就诊时可用的数据准确估计良好预后的概率和不良预后的风险。经过进一步验证后,该模型可能有助于选择适合手术清除血肿的患者。