Bodylska Weronika, Fandzloch Marzena, Szukiewicz Rafał, Lukowiak Anna
Institute of Low Temperature and Structure Research, Polish Academy of Sciences, Okólna 2, 50-422 Wrocław, Poland.
Faculty of Physics and Astronomy, University of Wrocław, pl. M. Borna 9, 50-204 Wrocław, Poland.
Nanomaterials (Basel). 2022 Dec 18;12(24):4480. doi: 10.3390/nano12244480.
Ascorbic acid (AA) is an important biomolecule, the deficiency or maladjustment of which is associated with the symptoms of many diseases (e.g., cardiovascular disease or cancer). Therefore, there is a need to develop a fluorescent probe capable of detecting AA in aqueous media. Here, we report the synthesis, structural, and spectroscopic characterization (by means of, e.g., XRD, XPS, IR and Raman spectroscopy, TG, SEM, and EDS analyses), as well as the photoluminescent properties of a metal-organic framework (MOF) based on Cu and Eu ions. The ion-exchange process of the extraframework cation in anionic Cu-based MOF is proposed as an appropriate strategy to obtain a new material with a nondisturbed structure and a sensitivity to interaction with AA. Accordingly, a novel Eu[Cu(μ-OH)(μ-4-carboxypyrazolato)] compound for the selective optical detection of AA with a short detection time of 5 min is described.
抗坏血酸（AA）是一种重要的生物分子，其缺乏或失调与许多疾病（如心血管疾病或癌症）的症状相关。因此，需要开发一种能够在水性介质中检测AA的荧光探针。在此，我们报告了一种基于铜和铕离子的金属有机框架（MOF）的合成、结构和光谱表征（例如通过XRD、XPS、IR和拉曼光谱、TG、SEM和EDS分析）以及光致发光性质。提出在阴离子型铜基MOF中进行骨架外阳离子的离子交换过程，作为获得具有未受干扰结构且对与AA相互作用敏感的新材料的合适策略。相应地，描述了一种用于选择性光学检测AA的新型铕[铜（μ-羟基）（μ-4-羧基吡唑）]化合物，其检测时间短，仅为5分钟。
