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猫视网膜和外侧膝状核中方向调谐的线性机制。

Linear mechanism of orientation tuning in the retina and lateral geniculate nucleus of the cat.

作者信息

Soodak R E, Shapley R M, Kaplan E

机构信息

Rockefeller University, New York, New York 10021.

出版信息

J Neurophysiol. 1987 Aug;58(2):267-75. doi: 10.1152/jn.1987.58.2.267.

DOI:10.1152/jn.1987.58.2.267
PMID:3655866
Abstract
  1. The orientation tuning of lateral geniculate nucleus (LGN) neurons and retinal ganglion cells (recorded as S potentials in the LGN) was investigated with drifting grating stimuli. 2. Results were compared with a quantitative model, in which receptive fields were constructed from linear, elliptical Gaussian center and surround subunits, and responses could be predicted to gratings of any spatial frequency at any orientation. 3. The orientation tuning of X and Y retinal ganglion cells and LGN neurons was shown to result from the linear mechanism of receptive-field elongation, as data from these cells could be well fit with this model. 4. The responses of LGN neurons and their input retinal ganglion cells were compared. The orientation tuning of LGN neurons was found to be a reflection of the tuning of their retinal inputs, showing that neither intrageniculate neural interactions nor the corticogeniculate projection play any role in LGN orientation selectivity.
摘要
  1. 利用漂移光栅刺激研究了外侧膝状体核(LGN)神经元和视网膜神经节细胞(在LGN中记录为S电位)的方向调谐。2. 将结果与定量模型进行比较,在该模型中,感受野由线性、椭圆形高斯中心和周边亚基构建而成,并且可以预测对任何方向上任何空间频率光栅的反应。3. X和Y视网膜神经节细胞以及LGN神经元的方向调谐被证明是由感受野伸长的线性机制导致的,因为这些细胞的数据可以很好地拟合该模型。4. 比较了LGN神经元及其输入视网膜神经节细胞的反应。发现LGN神经元的方向调谐是其视网膜输入调谐的反映,表明膝状体内神经相互作用和皮质膝状体投射在LGN方向选择性中均不起任何作用。

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