Research Center of Brain and Cognitive Neuroscience, Liaoning Normal University, Dalian 116029, P. R. China.
Key Laboratory of Brain and Cognitive Neuroscience, Liaoning Province, Dalian 116029, P. R. China.
Cereb Cortex. 2023 May 9;33(10):6345-6353. doi: 10.1093/cercor/bhac508.
Converging evidence has found that the perceived visual size illusions are heritable, raising the possibility that visual size illusions might be predicted by intrinsic brain activity without external stimuli. Here we measured resting-state brain activity and 2 classic visual size illusions (i.e. the Ebbinghaus and the Ponzo illusions) in succession, and conducted spectral dynamic causal modeling analysis among relevant cortical regions. Results revealed that forward connection from right V1 to superior parietal lobule (SPL) was predictive of the Ebbinghaus illusion, and self-connection in the right SPL predicted the Ponzo illusion. Moreover, disruption of intrinsic activity in the right SPL by repetitive transcranial magnetic stimulation (TMS) temporally increased the Ebbinghaus rather than the Ponzo illusion. These findings provide a better mechanistic understanding of visual size illusions by showing the causal and distinct contributions of right parietal cortex to them, and suggest that spontaneous fluctuations in intrinsic brain activity are relevant to individual difference in behavior.
越来越多的证据表明，感知到的视错觉是可以遗传的，这就使得无需外部刺激，仅凭内在的大脑活动来预测视错觉成为可能。在这里，我们连续测量了静息状态下的大脑活动和两种经典的视错觉（即艾宾浩斯错觉和庞佐错觉），并在相关皮质区域之间进行了频谱动态因果建模分析。结果表明，右侧 V1 到顶叶上回（SPL）的前向连接可以预测艾宾浩斯错觉，而右侧 SPL 的自连接可以预测庞佐错觉。此外，通过重复经颅磁刺激（TMS）对右侧 SPL 的内在活动进行干扰，会暂时增加艾宾浩斯错觉，而不是庞佐错觉。这些发现通过显示右侧顶叶皮层对这些错觉的因果贡献和独特贡献，为视觉大小错觉提供了更好的机制理解，并表明内在大脑活动的自发波动与行为个体差异有关。
