Department of Medical Education, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Vasco de Quiroga #15, Belisario Domínguez Sección XVI, Tlalpan, Mexico City, Mexico14080.
Metabolic Diseases Research Unit, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Vasco de Quiroga #15, Belisario Domínguez Sección XVI, Tlalpan, Mexico City, Mexico14080.
Trans R Soc Trop Med Hyg. 2023 May 2;117(5):383-390. doi: 10.1093/trstmh/trac123.
Healthcare saturation has been a prominent worry during the COVID-19 pandemic. Increase of hospital beds with mechanical ventilators has been central in Mexico's approach, but it is not known whether this actually improves access to care and the resulting quality of it. This study aimed to determine the impact of healthcare strain and other pre-specified variables on dying from coronavirus disease 2019 (COVID-19) without receiving invasive mechanical ventilation (IMV).
A retrospective cohort study was conducted using open data from Mexico City between 8 May 2020 and 5 January 2021. We performed Cox proportional hazards models to identify the strength of the association between proposed variables and the outcomes.
Of 33 797 hospitalized patients with suspected or confirmed COVID-19, 19 820 (58.6%) did not require IMV and survived, 5414 (16.1%) required IMV and were intubated and 8563 (25.3%) required IMV but died without receiving it. A greater occupation of IMV-capable beds increased the hazard of death without receiving IMV (hazard ratio [HR] 1.56, comparing 90% with 50% occupation). Private healthcare was the most protective factor for death without IMV (HR 0.14).
Higher hospital bed saturation increased the hazard of dying without being intubated and worsened the outcomes among mechanically ventilated patients. Older age also increased the hazard of the outcomes, while private healthcare dramatically decreased them.
在 COVID-19 大流行期间,医疗资源饱和一直是一个令人担忧的问题。增加带机械呼吸机的医院床位是墨西哥方法的核心,但目前尚不清楚这是否实际上改善了获得医疗服务的机会和由此产生的医疗服务质量。本研究旨在确定医疗压力和其他预先指定的变量对未接受有创机械通气(IMV)而死于 2019 年冠状病毒病(COVID-19)的影响。
使用 2020 年 5 月 8 日至 2021 年 1 月 5 日期间墨西哥城公开数据进行回顾性队列研究。我们使用 Cox 比例风险模型来确定提出的变量与结果之间的关联强度。
在 33797 名疑似或确诊 COVID-19 的住院患者中,有 19820 名(58.6%)不需要 IMV 且存活,5414 名(16.1%)需要 IMV 并进行插管,8563 名(25.3%)需要 IMV 但未接受 IMV 治疗而死亡。IMV 能力床位占用率的增加增加了未接受 IMV 治疗而死亡的风险(比较 90%和 50%床位占用率时,风险比 [HR] 为 1.56)。私立医疗保健是避免接受 IMV 治疗而死亡的最保护因素(HR 为 0.14)。
较高的医院床位饱和度增加了未经插管而死亡的风险,并恶化了接受机械通气患者的预后。年龄较大也增加了结果的风险,而私立医疗保健则大大降低了风险。