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对于腰椎狭窄症合并弥漫性特发性骨肥厚延伸至腰椎节段的患者,采用微创减压术可降低再次手术的风险:对两个回顾性队列的分析。

Less-invasive decompression procedures can reduce risk of reoperation for lumbar spinal stenosis with diffuse idiopathic skeletal hyperostosis extended to the lumbar segment: analysis of two retrospective cohorts.

机构信息

Department of Orthopaedic Surgery, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan.

Department of Orthopaedic Surgery, Osaka Metropolitan University, Osaka City, Osaka, Japan.

出版信息

Eur Spine J. 2023 Feb;32(2):505-516. doi: 10.1007/s00586-022-07496-1. Epub 2022 Dec 26.

Abstract

PURPOSE

Clinical outcomes after decompression procedures are reportedly worse for lumbar spinal stenosis (LSS) with diffuse idiopathic skeletal hyperostosis (DISH), especially DISH extended to the lumbar segment (L-DISH). However, no studies have compared the effect of less-invasive surgery versus conventional decompression techniques for LSS with DISH. The purpose of this study was to compare the long-term risk of reoperation after decompression surgery focusing on LSS with L-DISH.

METHODS

This study compared open procedure cohort (open conventional fenestration) and less-invasive procedure cohort (bilateral decompression via a unilateral approach) with ≥ 5 years of follow-up. After stratified analysis by L-DISH, patients with L-DISH were propensity score-matched by age and sex.

RESULTS

There were 57 patients with L-DISH among 489 patients in the open procedure cohort and 41 patients with L-DISH among 297 patients in the less-invasive procedure cohort. The reoperation rates in L-DISH were higher in the open than less-invasive procedure cohort for overall reoperations (25% and 7%, p = 0.026) and reoperations at index levels (18% and 5%, p = 0.059). Propensity score-matched analysis in L-DISH demonstrated that open procedures were significantly associated with increased overall reoperations (hazard ratio [HR], 6.18; 95% confidence interval [CI], 1.37-27.93) and reoperations at index levels (HR, 4.80; 95% CI, 1.04-22.23); there was no difference in reoperation at other lumbar levels.

CONCLUSIONS

Less-invasive procedures had a lower risk of reoperation, especially at index levels for LSS with L-DISH. Preserving midline-lumbar posterior elements could be desirable as a decompression procedure for LSS with L-DISH.

摘要

目的

据报道,弥漫性特发性骨肥厚(DISH)合并腰椎管狭窄症(LSS)患者行减压术后的临床结果较差,尤其是 DISH 延伸至腰椎节段(L-DISH)的患者。然而,目前尚无研究比较微创手术与传统减压技术治疗 DISH 合并 LSS 的效果。本研究旨在比较减压术后再次手术的长期风险,重点关注 L-DISH 合并 LSS 的患者。

方法

本研究比较了随访时间≥5 年的开放手术组(开放常规开窗术)和微创手术组(单侧入路双侧减压)。根据 L-DISH 进行分层分析后,对 L-DISH 患者按年龄和性别进行倾向评分匹配。

结果

开放手术组中 489 例患者中有 57 例为 L-DISH,微创手术组中 297 例患者中有 41 例为 L-DISH。L-DISH 患者中,开放手术组的总体再手术率(25%和 7%,p=0.026)和指数水平再手术率(18%和 5%,p=0.059)均高于微创手术组。在 L-DISH 患者中进行倾向评分匹配分析显示,开放手术与总体再手术(风险比[HR],6.18;95%置信区间[CI],1.37-27.93)和指数水平再手术(HR,4.80;95% CI,1.04-22.23)显著相关;其他腰椎水平的再手术无差异。

结论

微创手术治疗 L-DISH 合并 LSS 的再手术风险较低,尤其是在指数水平。保留中线-腰椎后柱结构可能是治疗 L-DISH 合并 LSS 的理想减压方法。

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