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弥漫性特发性骨肥厚症合并腰椎管狭窄后路腰椎体间融合的有限元分析

The Effect of Posterior Lumbar Interbody Fusion in Lumbar Spine Stenosis with Diffuse Idiopathic Skeletal Hyperostosis: A Finite Element Analysis.

机构信息

Department of Orthopedic Surgery, Yamaguchi University Graduate School of Medicine, Ube City, Yamaguchi Prefecture, Japan.

Engineering Center for Orthopaedic Research Excellence (E-CORE), Departments of Bioengineering and Orthopaedics, The University of Toledo, Toledo, Ohio, USA.

出版信息

World Neurosurg. 2023 Aug;176:e371-e379. doi: 10.1016/j.wneu.2023.05.063. Epub 2023 May 24.

Abstract

OBJECTIVE

Lumbar spinal canal stenosis (LSS) with diffuse idiopathic skeletal hyperostosis (DISH) can require revision surgery because of the intervertebral instability after decompression. However, there is a lack of mechanical analyses for decompression procedures for LSS with DISH.

METHODS

This study used a validated, three-dimensional finite element model of an L1-L5 lumbar spine, L1-L4 DISH, pelvis, and femurs to compare the biomechanical parameters (range of motion [ROM], intervertebral disc, hip joint, and instrumentation stresses) with an L5-sacrum (L5-S) and L4-S posterior lumbar interbody fusion (PLIF). A pure moment with a compressive follower load was applied to these models.

RESULTS

ROM of L5-S and L4-S PLIF models decreased by more than 50% at L4-L5, respectively, and decreased by more than 15% at L1-S compared with the DISH model in all motions. The L4-L5 nucleus stress of the L5-S PLIF increased by more than 14% compared with the DISH model. In all motions, the hip stress of DISH, L5-S, and L4-S PLIF had very small differences. The sacroiliac joint stress of L5-S and L4-S PLIF models decreased by more than 15% compared with the DISH model. The stress values of the screws and rods in the L4-S PLIF model was higher than in the L5-S PLIF model.

CONCLUSIONS

The concentration of stress because of DISH may influence adjacent segment disease on the nonunited segment of PLIF. A shorter-level lumbar interbody fixation is recommended to preserve ROM; however, it should be used with caution because it could provoke adjacent segment disease.

摘要

目的

腰椎管狭窄症(LSS)伴弥漫性特发性骨肥厚(DISH)减压后可因节段间不稳定而需要翻修手术。然而,DISH 合并 LSS 的减压手术缺乏力学分析。

方法

本研究采用了一种已验证的 L1-L5 腰椎、L1-L4 DISH、骨盆和股骨的三维有限元模型,比较了生物力学参数(活动度[ROM]、椎间盘、髋关节和器械应力)与 L5-骶骨(L5-S)和 L4-骶骨(L4-S)后路腰椎体间融合(PLIF)的差异。这些模型施加了一个纯力矩和一个压缩跟随载荷。

结果

与 DISH 模型相比,L5-S 和 L4-S PLIF 模型在 L4-L5 处的 ROM 分别减少了 50%以上,在所有运动中在 L1-S 处减少了 15%以上。与 DISH 模型相比,L5-S PLIF 的 L4-L5 核应力增加了 14%以上。在所有运动中,DISH、L5-S 和 L4-S PLIF 的髋关节应力差异很小。L5-S 和 L4-S PLIF 模型的骶髂关节应力比 DISH 模型减少了 15%以上。L4-S PLIF 模型中螺钉和棒的应力值高于 L5-S PLIF 模型。

结论

DISH 导致的应力集中可能会影响 PLIF 非融合节段的邻近节段疾病。建议采用较短节段的腰椎体间固定来保留 ROM;然而,由于可能引发邻近节段疾病,应谨慎使用。

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