Chau Matthew, Swarbrick Nicole, Lee Sunny
Department of Urology, Royal Perth Hospital, Perth, WA, Australia.
Department of Anatomical Pathology, Path West Laboratory Medicine, Perth, WA, Australia.
Urol Case Rep. 2022 Dec 12;46:102300. doi: 10.1016/j.eucr.2022.102300. eCollection 2023 Jan.
Penile metastases are a rare entity and are associated with widespread metastatic disease. It is associated with significant morbidity with a poor prognosis. There have been few case reports about metastatic prostate adenocarcinoma to the penis. Diagnosis is often clinical, however, the use of PSMA PET has a high sensitivity. We report the first case of metastatic castration resistant prostate cancer with an isolated penile metastatic site. This was not identified on conventional staging or PSMA PET, but using FDG PET. A radical penectomy was performed with ongoing survival.
阴茎转移瘤是一种罕见的疾病,与广泛的转移性疾病相关。它与严重的发病率和不良预后相关。关于前列腺腺癌转移至阴茎的病例报告很少。诊断通常依靠临床症状,然而,使用前列腺特异性膜抗原(PSMA)正电子发射断层扫描(PET)具有很高的敏感性。我们报告了首例孤立性阴茎转移灶的去势抵抗性前列腺癌转移病例。该病例在传统分期或PSMA PET检查中均未发现,但通过氟代脱氧葡萄糖(FDG)PET检查得以确诊。患者接受了根治性阴茎切除术,目前仍存活。