[Change in the functional indices of animals during prolonged inhalation of acetic acid].

Laboratory animals inhaled acetic acid vapors at a concentration of 86 to 27 mg/m3 for 3 to 35 days. It was found that the dose 36 mg/m3 inhaled for as long as 22 days constituted the minimal acting dose. The most sensitive parameters to be used in detecting the toxic effect of acetic acid were: treadmill run duration, open field activity, and ethylene, acetaldehyde and acetone concentrations in the exhaled air.