Shishkina V V, Piperkova E I, Okulov L V
Med Radiol (Mosk). 1987 Oct;32(10):26-31.
Esophagoscintigraphy with labeled liquid and solid food was performed in 34 patients without subjective complaints and signs of disease of the esophagus in the patient history permitting the determination of quantitative and qualitative characteristics of normal motor-evacuatory function of the esophagus and lower esophageal sphincter (LES) under the most physiological conditions using mixtures of labeled natural food ingredients as compared to routine methods. In esophageal transit time (ETT) over 5 sec., a clearance value below 87.2% and passage rate below 21.6% for liquids, and ETT over 9 sec., a clearance value of 86.6% and passage rate less than 11.39% respectively for solid food disorders of esophageal and/or LES motor function were noted. Normal oropharyngeal time was 1.5-2 sec. A total of 46 patients with esophageal cancer and stomach cancer with the involvement of the esophagus before treatment were examined. In cancer of the esophagus its function depended on a tumor site and stage. In order to raise diagnostic sensitivity dynamic esophagoscintigraphy should be performed using liquid and solid food because during liquid passage a study with a hard bolus of patients with severe esophageal dysfunction showed that in 36.9% of the patients the quantitative and qualitative indices were within normal. Radionuclide methods permit the determination of the level of a pathological focus, a degree of esophageal permeability, quantitative characterization of a degree of disorder of esophageal function in order to raise the functional diagnosis of the esophagus and LES, and the determination of motor disorders at the earliest stages of tumor development.
对34例无食管主观不适及疾病史体征的患者进行了标记液体和固体食物的食管闪烁扫描,与常规方法相比,使用标记天然食物成分的混合物,在最生理条件下确定食管和食管下括约肌(LES)正常运动排空功能的定量和定性特征。在食管通过时间(ETT)超过5秒时,液体清除率低于87.2%,通过率低于21.6%;在ETT超过9秒时,固体食物的清除率为86.6%,通过率分别低于11.39%,提示食管和/或LES运动功能紊乱。正常口咽时间为1.5 - 2秒。共检查了46例治疗前食管癌和胃癌累及食管的患者。食管癌的功能取决于肿瘤部位和分期。为了提高诊断敏感性,应使用液体和固体食物进行动态食管闪烁扫描,因为在液体通过期间,对严重食管功能障碍患者进行硬团块研究表明,36.9%的患者定量和定性指标在正常范围内。放射性核素方法可以确定病理病灶的水平、食管通透性的程度、食管功能紊乱程度的定量特征,以提高食管和LES的功能诊断,并在肿瘤发展的最早阶段确定运动障碍。