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中国南疆边境地区绵羊和山羊中 的分布及分子流行病学研究。

Distribution and Molecular Epidemiology of in and Small Ruminants in Border Regions of South Xinjiang, China.

机构信息

College of Animal Science and Technology, Tarim University, Alar, People's Republic of China.

Engineering Laboratory of Tarim Animal Diseases Diagnosis and Control, Xinjiang Production & Construction Corps, Alar, People's Republic of China.

出版信息

Vector Borne Zoonotic Dis. 2023 Jan;23(1):1-8. doi: 10.1089/vbz.2022.0059. Epub 2022 Dec 23.


DOI:10.1089/vbz.2022.0059
PMID:36576898
Abstract

are obligate intracellular bacteria that can endanger human and animal health, and they can be transmitted by arthropod vectors, such as and ticks. In this study, 433 specimens, including 370 and 63 sheep blood samples, were collected from nine districts of South Xinjiang to investigate the distribution and molecular epidemiology of in and small ruminant. DNA of was detected in 109 (25.2%, 109/433) of the 433 samples using PCR and sequencing. The analysis of sequences revealed four different genotypes, including genotype III (47.7%; 52/109), GB3 (34.0%; 37/109), AoGOv3 (15.6%; 17/109), and XJ9 (2.8%; 3/109). To the best of our knowledge, genotypes GB3, AoGOv3, and XJ9 detected in this study are the first to be reported in , and our data indicate that XJ9 is a novel genotype presented herein for the first time. These findings provide important references for the new understanding and prevention of in border counties in China.

摘要

是专性细胞内细菌,可危害人类和动物健康,可通过节肢动物媒介,如 和蜱传播。本研究从新疆南部九个地区采集了 433 份标本,包括 370 份 和 63 份绵羊血样,以调查 和小反刍动物中 在中国的分布和分子流行病学。使用 PCR 和测序在 433 份样本中的 109 份(25.2%,109/433)中检测到 的 DNA。对 序列的分析显示了四种不同的基因型,包括基因型 III(47.7%,52/109)、GB3(34.0%,37/109)、AoGOv3(15.6%,17/109)和 XJ9(2.8%,3/109)。据我们所知,本研究中检测到的基因型 GB3、AoGOv3 和 XJ9 在中国 中首次报道,我们的数据表明 XJ9 是一种新型 基因型,在此首次提出。这些发现为了解和预防中国边境地区的 提供了重要参考。

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