• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

巴基斯坦的麻醉药品短缺:一项多中心全国性调查。

Anesthetic drug shortages in Pakistan: a multicentre nationwide survey.

机构信息

Aga Khan University Hospital, Karachi, Pakistan.

Department of Anaesthesiology, King Hammad International Hospital, Al Sayh, Bahrain.

出版信息

Can J Anaesth. 2023 Mar;70(3):335-342. doi: 10.1007/s12630-022-02381-3. Epub 2022 Dec 28.

DOI:10.1007/s12630-022-02381-3
PMID:36577892
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9797251/
Abstract

PURPOSE

There is a paucity of literature on anesthetic drug shortages and their impact on patient safety in lower-middle-income countries. We sought to determine the magnitude of the problem, the effect on patient care and safety, and the adverse patient outcomes witnessed by anesthesiologists in Pakistan METHODS: We conducted a nationwide, multicentre, cross-sectional survey of a representative sample of anesthesiologists in Pakistan (January 2021 to June 2021). The survey questionnaire was adapted from the American Society of Anesthesiologists (ASA) survey on drug shortages and was modified based on the national essential medication list 2018 of Pakistan. It was distributed through Google Forms to anesthesiologists practicing in both the private and government sector. The names of hospitals or the identity of anesthesiologists was not required. The questionnaire consisted of 20 items and focused on the anesthesiologists' experience of drug shortages, the availability of drugs, and the impact of drug shortages on their individual practice.

RESULTS

Two hundred and forty-six responses were received. Approximately 50% (122/246) of anesthesia practitioners in Pakistan reported anesthetic drug shortages. Fifty-seven percent of respondents mentioned using an inferior drug that may have significantly affected the delivery of anesthetic care. Four participants mentioned severe morbidity and another four mentioned observing a mortality associated with drug shortage.

CONCLUSION

Anesthetic drug shortages are common in anesthetic practice in Pakistan and they appear to affect patient care and outcomes.

摘要

目的

关于中低收入国家麻醉药物短缺及其对患者安全的影响,文献报道较少。我们旨在确定该问题的严重程度、对患者治疗和安全的影响,以及巴基斯坦麻醉师观察到的不良患者结局。

方法

我们对巴基斯坦有代表性的麻醉师样本进行了一项全国性、多中心、横断面调查(2021 年 1 月至 2021 年 6 月)。调查问卷改编自美国麻醉师协会(ASA)关于药物短缺的调查,并根据巴基斯坦 2018 年国家基本药物清单进行了修改。它通过 Google 表单分发给私营和政府部门的麻醉师。不需要提供医院或麻醉师的姓名。调查问卷由 20 个项目组成,重点关注麻醉师的药物短缺经验、药物的可获得性以及药物短缺对其个人实践的影响。

结果

共收到 246 份回复。约 50%(122/246)的巴基斯坦麻醉师报告存在麻醉药物短缺。57%的受访者提到使用了可能严重影响麻醉治疗的劣质药物。有 4 名参与者提到严重的发病率,另有 4 名参与者提到观察到与药物短缺相关的死亡率。

结论

麻醉药物短缺在巴基斯坦的麻醉实践中很常见,似乎会影响患者的治疗和结局。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e4f8/9797251/b319fe46fd3d/12630_2022_2381_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e4f8/9797251/b319fe46fd3d/12630_2022_2381_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e4f8/9797251/b319fe46fd3d/12630_2022_2381_Fig1_HTML.jpg

相似文献

1
Anesthetic drug shortages in Pakistan: a multicentre nationwide survey.巴基斯坦的麻醉药品短缺:一项多中心全国性调查。
Can J Anaesth. 2023 Mar;70(3):335-342. doi: 10.1007/s12630-022-02381-3. Epub 2022 Dec 28.
2
Drug shortages in Canadian anesthesia: a national survey.加拿大麻醉药物短缺:全国性调查。
Can J Anaesth. 2013 Jun;60(6):539-51. doi: 10.1007/s12630-013-9920-z. Epub 2013 Apr 2.
3
How Anesthesiologists Experience and Negotiate Ethical Challenges from Drug Shortages.麻醉医生如何应对药品短缺带来的伦理挑战并从中获得经验。
AJOB Empir Bioeth. 2021 Apr-Jun;12(2):84-91. doi: 10.1080/23294515.2020.1839596. Epub 2020 Oct 30.
4
Challenges of Anesthesia in Low- and Middle-Income Countries: A Cross-Sectional Survey of Access to Safe Obstetric Anesthesia in East Africa.低收入和中等收入国家的麻醉挑战:东非安全产科麻醉可及性的横断面调查
Anesth Analg. 2017 Jan;124(1):290-299. doi: 10.1213/ANE.0000000000001690.
5
Pharmacists' approach to oncology medicine shortages: results of a cross-sectional survey in Pakistan.药剂师应对肿瘤药物短缺的方法:巴基斯坦横断面调查的结果。
BMJ Open. 2023 Sep 18;13(9):e070634. doi: 10.1136/bmjopen-2022-070634.
6
Perceptions of pharmacists towards drug shortages in the healthcare system of Pakistan and its impact on patient care: findings from a cross-sectional survey.药剂师对巴基斯坦医疗体系中药物短缺的看法及其对患者护理的影响:一项横断面调查的结果。
BMJ Open. 2021 Dec 23;11(12):e050196. doi: 10.1136/bmjopen-2021-050196.
7
Drug shortages in large hospitals in Riyadh: a cross-sectional study.利雅得大型医院的药品短缺情况:一项横断面研究。
Ann Saudi Med. 2017 Sep-Oct;37(5):375-385. doi: 10.5144/0256-4947.2017.375.
8
Effects on patient care caused by drug shortages: a survey.药品短缺对患者护理的影响:一项调查。
J Manag Care Pharm. 2013 Nov-Dec;19(9):783-8. doi: 10.18553/jmcp.2013.19.9.783.
9
[Critical incidents during regional anesthesia in Japanese Society of Anesthesiologists-Certified Training Hospitals: an analysis of responses to the annual survey conducted between 1999 and 2002 by the Japanese Society of Anesthesiologists].[日本麻醉医师协会认证培训医院区域麻醉期间的严重事件:对日本麻醉医师协会1999年至2002年进行的年度调查回复的分析]
Masui. 2005 Apr;54(4):440-9.
10
Insights into European drug shortages: a survey of hospital pharmacists.欧洲药品短缺问题洞察:医院药剂师调查
PLoS One. 2015 Mar 16;10(3):e0119322. doi: 10.1371/journal.pone.0119322. eCollection 2015.

引用本文的文献

1
Surveying anesthesia care provision and deficiencies among the secondary public sector hospitals of rural Sindh, Pakistan.对巴基斯坦信德省农村地区二级公立医院的麻醉护理服务及不足之处进行调查。
Can J Anaesth. 2025 May 7. doi: 10.1007/s12630-025-02923-5.
2
Drug supply and assurance: a cross-sectional study of drug shortage monitoring varieties in China.药品供应与保障:中国药品短缺监测品种的横断面研究。
BMC Public Health. 2024 Jul 30;24(1):2048. doi: 10.1186/s12889-024-19361-5.
3
Equity, Diversity, and Inclusion in the Journal and the United Nations Sustainable Development Goals.

本文引用的文献

1
Drug Shortage: Causes, Impact, and Mitigation Strategies.药品短缺:原因、影响及缓解策略
Front Pharmacol. 2021 Jul 9;12:693426. doi: 10.3389/fphar.2021.693426. eCollection 2021.
2
Hyperoxia and Lungs: What We Have Learned From Animal Models.高氧与肺:我们从动物模型中学到了什么。
Front Med (Lausanne). 2021 Mar 9;8:606678. doi: 10.3389/fmed.2021.606678. eCollection 2021.
3
Universal access to essential medicines as part of the right to health: a cross-national comparison of national laws, medicines policies, and health system indicators.
本刊中的公平、多样性与包容性以及联合国可持续发展目标
Can J Anaesth. 2023 Jun;70(6):925-929. doi: 10.1007/s12630-023-02478-3. Epub 2023 May 15.
作为健康权的一部分,普及基本药物:对国家法律、药物政策和卫生系统指标的跨国比较。
Glob Health Action. 2020 Dec 31;13(1):1699342. doi: 10.1080/16549716.2019.1699342.
4
Misinformation in Wake of the COVID-19 Outbreak: Fueling Shortage and Misuse of Lifesaving Drugs in Pakistan.新冠疫情爆发后的错误信息:加剧巴基斯坦救命药物的短缺与滥用
Disaster Med Public Health Prep. 2021 Aug;15(4):e32-e33. doi: 10.1017/dmp.2020.400. Epub 2020 Oct 22.
5
Medicines shortages in Pakistan: a qualitative study to explore current situation, reasons and possible solutions to overcome the barriers.巴基斯坦药品短缺:一项探索现状、原因和可能解决方案以克服障碍的定性研究。
BMJ Open. 2019 Sep 4;9(9):e027028. doi: 10.1136/bmjopen-2018-027028.
6
Access to controlled medicines for anesthesia and surgical care in low-income countries: a narrative review of international drug control systems and policies.低收入国家获取用于麻醉和手术护理的管制药品:对国际药物管制系统和政策的叙述性综述
Can J Anaesth. 2017 Mar;64(3):296-307. doi: 10.1007/s12630-016-0805-9. Epub 2017 Jan 3.
7
Effects on patient care caused by drug shortages: a survey.药品短缺对患者护理的影响:一项调查。
J Manag Care Pharm. 2013 Nov-Dec;19(9):783-8. doi: 10.18553/jmcp.2013.19.9.783.
8
Access to essential medicines in Pakistan: policy and health systems research concerns.巴基斯坦基本药物的可及性:政策和卫生系统研究关注点。
PLoS One. 2013 May 22;8(5):e63515. doi: 10.1371/journal.pone.0063515. Print 2013.
9
Drug shortages in Canadian anesthesia: a national survey.加拿大麻醉药物短缺:全国性调查。
Can J Anaesth. 2013 Jun;60(6):539-51. doi: 10.1007/s12630-013-9920-z. Epub 2013 Apr 2.
10
Shortages of medicines: a complex global challenge.药品短缺:一项复杂的全球挑战。
Bull World Health Organ. 2012 Mar 1;90(3):158-158A. doi: 10.2471/BLT.11.101303.