患有脑梗死的POEMS综合征患者在出现多发性神经病之前预后较好。
Better prognosis in POEMS patients with cerebral infarction before polyneuropathy.
作者信息
Lan Xiaoxi, Sun Wanling, Guo Yixian, Chang Xiaoli, Wang Guoxiang, Hu Ronghua
机构信息
Xuanwu Hospital Capital Medical University, Beijing 100053, China.
出版信息
Heliyon. 2022 Dec 13;8(12):e12201. doi: 10.1016/j.heliyon.2022.e12201. eCollection 2022 Dec.
POEMS syndrome is a plasma cell disease. Clinical manifestations and clinical onset are variable. In recent years, more and more cases of POEMS syndrome with cerebrovascular disease and ischemic stroke have been reported. However, it is rare for patients with POEMS syndrome to present with a cerebrovascular accident as the first clinical manifestation. We presented three cases of POEMS syndrome with cerebral infarction in different phases of the disease. We then searched the literature for studies involving POEMS syndrome complicated with cerebral infarction. There were 81 cases in total. In nine patients, cerebral infarctions occurred before polyneuropathy. Patients with cerebral infarction before polyneuropathy have better prognosis of POEMS than those with cerebral infarction after polyneuropathy.
POEMS综合征是一种浆细胞疾病。其临床表现和临床起病情况各不相同。近年来，越来越多关于POEMS综合征合并脑血管疾病和缺血性卒中的病例被报道。然而，以脑血管意外作为首发临床表现的POEMS综合征患者较为罕见。我们报告了3例处于疾病不同阶段的POEMS综合征合并脑梗死的病例。然后我们检索了文献中有关POEMS综合征合并脑梗死的研究。总共81例。9例患者在多发性神经病之前发生脑梗死。多发性神经病之前发生脑梗死的POEMS综合征患者比多发性神经病之后发生脑梗死的患者预后更好。
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