副肿瘤性进行性血管病作为多神经病、器官肿大、内分泌病或水肿、M蛋白峰及皮肤表现的首发表现：一例报告
Paraneoplastic Progressive Vasculopathy as the Presenting Manifestation of Polyneuropathy, Organomegaly, Endocrinopathy or Edema, M-Spike, and Skin Manifestations: A Case Report.
作者信息
Yaghi Shadi, Elkind Mitchell S V
机构信息
Department of Neurology, The Warren Alpert Medical School of Brown University, Providence, Rhode Island.
Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, New York; Department of Epidemiology, Mailman School of Public Health, Columbia University Medical Center, New York, New York.
出版信息
J Stroke Cerebrovasc Dis. 2016 Jul;25(7):e103-e107. doi: 10.1016/j.jstrokecerebrovasdis.2016.03.014. Epub 2016 May 10.
Polyneuropathy, organomegaly, endocrinopathy or edema, M-spike, and skin manifestations (POEMS) syndrome is a rare multisystem disease. There are very few reports of stroke as the presenting manifestation of POEMS. We report a patient with ischemic stroke due to an underlying vasculopathy as the initial presentation of POEMS. This case highlights the importance of recognizing ischemic stroke as a presenting sign for POEMS as early diagnosis and treatment in patients with POEMS may prevent progression of multisystem involvement and may potentially stabilize the vasculopathy associated with it.
多神经病、器官肿大、内分泌病或水肿、M蛋白峰及皮肤表现（POEMS）综合征是一种罕见的多系统疾病。以中风作为POEMS首发表现的报道非常少。我们报告1例因潜在血管病变导致缺血性中风作为POEMS初始表现的患者。该病例强调了将缺血性中风识别为POEMS首发体征的重要性，因为对POEMS患者进行早期诊断和治疗可能会防止多系统受累的进展，并可能稳定与之相关的血管病变。
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