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惊恐障碍患者肥厚型梗阻性心肌病的筛查:一例报告

Screening for Hypertrophic Obstructive Cardiomyopathy in Patients With Panic Disorder: A Case Report.

作者信息

Bonitz Thomas, Scypinski Luke, Chin Justin, Lomiguen Christine M

机构信息

Medical Education, Lake Erie College of Osteopathic Medicine, Erie, USA.

Family Medicine, LifeLong Medical Care, Richmond, USA.

出版信息

Cureus. 2022 Nov 23;14(11):e31811. doi: 10.7759/cureus.31811. eCollection 2022 Nov.

Abstract

Hypertrophic obstructive cardiomyopathy (HOCM) is a cardiovascular disease that is widely recognized as an important cause of various cardiovascular pathologies. Passed through an autosomal dominant inheritance pattern, mutations can result in cardiac dysfunction that can manifest in dyspnea, exercise intolerance, and sudden death. Panic disorder can present similarly to HOCM; however, precautions and treatment differ significantly. Here, we present a case of a 56-year-old male with a history of panic disorder who presented to the emergency department with recurrent episodes of palpitations, lightheadedness, and dyspnea, and who was subsequently hospitalized due to new ventricular tachyarrhythmia and diagnosed with HOCM. This case highlights the importance of detailed history taking, follow-up of chronic symptoms, and consideration of genetic screening for HOCM in patients with panic disorder.

摘要

肥厚型梗阻性心肌病(HOCM)是一种心血管疾病,被广泛认为是各种心血管病变的重要原因。通过常染色体显性遗传模式,突变可导致心脏功能障碍,表现为呼吸困难、运动不耐受和猝死。惊恐障碍的表现可能与HOCM相似;然而,预防措施和治疗方法有显著差异。在此,我们报告一例56岁男性病例,该患者有惊恐障碍病史,因反复发作心悸、头晕和呼吸困难就诊于急诊科,随后因新发室性心律失常住院并被诊断为HOCM。该病例强调了详细询问病史、对慢性症状进行随访以及对惊恐障碍患者考虑进行HOCM基因筛查的重要性。

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