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海分枝杆菌皮肤感染:三例病例系列及文献综述

Mycobacterium marinum Cutaneous Infection: A Series of Three Cases and Literature Review.

作者信息

Gonçalves Inês C, Furtado Isabel, Gonçalves Maria João, Xará Sandra

机构信息

Infectious Disease, Centro Hospitalar e Universitário do Porto, Porto, PRT.

Infectious Disease, Hospital Pedro Hispano, Matosinhos, PRT.

出版信息

Cureus. 2022 Nov 22;14(11):e31787. doi: 10.7759/cureus.31787. eCollection 2022 Nov.

DOI:10.7759/cureus.31787
PMID:36579262
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9780696/
Abstract

is a non-tuberculous mycobacteria present in natural and non-chlorinated bodies of water. It is a known fish pathogen but can also cause human disease. It usually causes cutaneous lesions but in rare cases may originate more invasive diseases with the involvement of deep structures. We describe three cases of patients with cutaneous infection by evaluated in a tertiary care center, two with confirmed infection and one with a presumptive diagnosis based on clinical and epidemiological features. A brief bibliographic review of infections is then presented to support the theme. We aim to alert one to the difficulties in establishing the correct diagnosis of this infection, emphasize the importance of a high degree of suspicion for its identification, and review the therapeutic management options.

摘要

是一种存在于天然和未氯化水体中的非结核分枝杆菌。它是一种已知的鱼类病原体,但也可导致人类疾病。它通常引起皮肤病变,但在罕见情况下可能引发更具侵袭性的疾病并累及深部结构。我们描述了在一家三级医疗中心评估的三例皮肤感染患者,其中两例确诊感染,一例根据临床和流行病学特征进行了推定诊断。随后对感染进行了简要的文献综述以支持该主题。我们旨在提醒人们注意建立这种感染正确诊断的困难,强调高度怀疑对其识别的重要性,并回顾治疗管理选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fda5/9780696/305d3431b85d/cureus-0014-00000031787-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fda5/9780696/cd41f17c8711/cureus-0014-00000031787-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fda5/9780696/0a6cf910756d/cureus-0014-00000031787-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fda5/9780696/305d3431b85d/cureus-0014-00000031787-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fda5/9780696/cd41f17c8711/cureus-0014-00000031787-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fda5/9780696/0a6cf910756d/cureus-0014-00000031787-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fda5/9780696/305d3431b85d/cureus-0014-00000031787-i03.jpg

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本文引用的文献

1
Occurrence of spp. in ornamental fish.观赏鱼中 spp. 的出现情况。
Ann Agric Environ Med. 2020 Dec 22;27(4):535-539. doi: 10.26444/aaem/114913. Epub 2019 Dec 9.
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Mycobacterium marinum lymphocutaneous infection.海分支杆菌淋巴皮肤感染
Dermatol Online J. 2019 Feb 15;25(2):13030/qt5bb78905.
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Cutaneous Mycobacterial Infections.皮肤分枝杆菌感染。
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Twenty-eight cases of Mycobacterium marinum infection: retrospective case series and literature review.28例海分枝杆菌感染:回顾性病例系列研究及文献综述
Infection. 2015 Dec;43(6):655-62. doi: 10.1007/s15010-015-0776-8. Epub 2015 Apr 14.
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Treatment of Mycobacterium marinum cutaneous infections.海分枝杆菌皮肤感染的治疗。
Expert Opin Pharmacother. 2007 Dec;8(17):2965-78. doi: 10.1517/14656566.8.17.2965.
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An official ATS/IDSA statement: diagnosis, treatment, and prevention of nontuberculous mycobacterial diseases.美国胸科学会/美国感染病学会官方声明:非结核分枝杆菌病的诊断、治疗与预防
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Fish tank exposure and cutaneous infections due to Mycobacterium marinum: tuberculin skin testing, treatment, and prevention.鱼缸接触与海分支杆菌引起的皮肤感染:结核菌素皮肤试验、治疗及预防
Clin Infect Dis. 2003 Aug 1;37(3):390-7. doi: 10.1086/376628. Epub 2003 Jul 18.
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Incubation period and sources of exposure for cutaneous Mycobacterium marinum infection: case report and review of the literature.皮肤海分枝杆菌感染的潜伏期和暴露源:病例报告及文献综述
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