鹅去氧胆酸短期给药后的降甘油三酯作用
Hypotriglyceridemic effect of chenodeoxycholic acid after a short time of administration.
作者信息
Camarri E, Marcolongo R, Fici F
出版信息
Int J Clin Pharmacol Biopharm. 1978 Nov;16(11):527-8.
PMID:365797
Abstract
Administration of chenodeoxycholic acid (CDCA), 200 mg/day, for 5 days to patients with primary hypertriglyceridemia reduced by 34% the serum triglycerides concentration. Reduction after CDCA is statistically significant vs. the placebo. Even after a short time of CDCA administration, the pharmacological effect is clearly evident.
摘要
对原发性高甘油三酯血症患者给予鹅去氧胆酸（CDCA），剂量为每日200毫克，持续5天，可使血清甘油三酯浓度降低34%。与安慰剂相比，服用CDCA后的降低具有统计学意义。即使在服用CDCA的短时间后，药理作用也明显可见。
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