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间歇性高强度运动对高血压前期至确诊高血压的影响:一项系统评价和荟萃分析。

Intermittent high-intensity exercise for pre- to established hypertension: A systematic review and meta-analysis.

作者信息

Teixeira Jorge M M, Motta-Santos Daisy, Milanovic Zoran, Pereira Rita L, Krustrup Peter, Póvoas Susana

机构信息

Research Center in Sports Sciences, Health Sciences and Human Development (CIDESD), University of Maia, Maia, Portugal.

Sports Department, School of Physical Education, Physiotherapy and Occupational Therapy, Federal University of Minas Gerais, Belo Horizonte, Brazil.

出版信息

Scand J Med Sci Sports. 2023 Apr;33(4):364-381. doi: 10.1111/sms.14299. Epub 2023 Jan 16.

DOI:10.1111/sms.14299
PMID:36579740
Abstract

OBJECTIVE

To determine the impact of intermittent high-intensity exercise training ([IHIE], including high-intensity interval training [HIIT] and recreational team sports [RTS]) on systolic (SBP) and diastolic blood pressure (DBP) in adults with pre- to established arterial hypertension.

DATA SOURCES

MEDLINE, Cochrane Library, Embase, and SPORTDiscus.

ELIGIBILITY CRITERIA

Randomized controlled trials (RCTs) comparing the impact of IHIE on BP versus a non-exercise control.

DATA COLLECTION AND ANALYSIS

Two authors independently conducted all procedures. Mean differences were calculated using random-effects model. The certainty of the evidence was assessed with GRADE.

RESULTS

Twenty-seven RCTs (18 HIIT and 9 RTS) were analyzed, with median duration of 12 weeks. Participants' (n = 946) median age was 46 years. Overall, IHIE decreased SBP (-3.29 mmHg; 95% CI: -5.19, -1.39) and DBP (-2.62 mmHg; 95% CI: -3.79, -1.44) compared to the control group. IHIE elicited higher decreases in office SBP and DBP of hypertensive subjects (SBP: -7.13 mmHg, [95% CI: -10.12, -4.15]; DBP: -5.81 mmHg, [95% CI: -7.94, -3.69]) than pre-hypertensive (SBP: -2.14 mmHg, [95% CI: -4.36, -0.08]; DBP: -1.83 mmHg, [95% CI: -2.99, -0.67]). No significant differences were found between HIIT (SBP: -2.12 mmHg, [95% CI: -4.78, -0.54]; DBP: -1.89 mmHg, [95% CI: -3.32, -0.48]) and RTS (SBP: -4.18 mmHg, [95% CI: -7.19, -2.43]; DBP: -4.04 mmHg, [95% CI: -6.00, -2.09]). These findings present low/very low certainty of evidence. No adverse cardiovascular events were reported.

CONCLUSIONS

IHIE appears to be safe and to promote substantial decreases in BP, particularly in patients with hypertension. However, the certainty of evidence was low/very low.

PROTOCOL

CRD42020163575.

摘要

目的

确定间歇性高强度运动训练([IHIE],包括高强度间歇训练[HIIT]和休闲团队运动[RTS])对患有前期至确诊动脉高血压的成年人收缩压(SBP)和舒张压(DBP)的影响。

数据来源

MEDLINE、Cochrane图书馆、Embase和SPORTDiscus。

纳入标准

比较IHIE对血压影响与非运动对照组的随机对照试验(RCT)。

数据收集与分析

两位作者独立进行所有程序。使用随机效应模型计算平均差异。采用GRADE评估证据的确定性。

结果

分析了27项RCT(18项HIIT和9项RTS),中位持续时间为12周。参与者(n = 946)的中位年龄为46岁。总体而言,与对照组相比,IHIE降低了SBP(-3.29 mmHg;95% CI:-5.19,-1.39)和DBP(-2.62 mmHg;95% CI:-3.79,-1.44)。与高血压前期患者(SBP:-2.14 mmHg,[95% CI:-4.36,-0.08];DBP:-1.83 mmHg,[95% CI:-2.99,-0.67])相比,IHIE使高血压患者的诊室SBP和DBP下降幅度更大(SBP:-7.13 mmHg,[95% CI:-10.12,-4.15];DBP:-5.81 mmHg,[95% CI:-7.94,-3.69])。HIIT(SBP:-2.12 mmHg,[95% CI:-4.78,-0.54];DBP:-1.89 mmHg,[95% CI:-3.32,-0.48])和RTS(SBP:-4.18 mmHg,[95% CI:-7.19,-2.43];DBP:-4.04 mmHg,[95% CI:-6.00,-2.09])之间未发现显著差异。这些发现的证据确定性为低/极低。未报告不良心血管事件。

结论

IHIE似乎是安全的,并能显著降低血压,尤其是高血压患者。然而,证据的确定性为低/极低。

方案编号

CRD42020163575。

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