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[牛磺酸对七鳃鳗脊髓运动神经元的抑制作用]

[Inhibitory effects of taurine on spinal cord motoneurons of the lamprey].

作者信息

Batueva I V, Veselkin N P, Suderevskaia E I

出版信息

Neirofiziologiia. 1987;19(4):551-4.

PMID:3658043
Abstract

The influence of bath application of taurine (1-10 X 10(-4) mol/l) on the activity of motoneurons was studied in the isolated lamprey spinal cord. EPSPs evoked by stimulation of the descending tract as well as unitary EPSPs evoked by intracellular depolarization of the individual Müller axons were depressed, whereas conduction of action potentials in the Müller axons and antidromic action potentials of motoneurons were practically unchanged. A deep depression of electrical, in addition to chemical, components of EPSPs and comparison of the obtained results with the available morphological data on the structure of reticulomotor synapses in lamprey, allow concluding that the inhibitory synapses can be located near the excitatory ones on the motoneuron dendrites.

摘要

在离体七鳃鳗脊髓中研究了浴缸应用牛磺酸(1 - 10×10⁻⁴mol/L)对运动神经元活性的影响。刺激下行束诱发的兴奋性突触后电位(EPSPs)以及单个米勒轴突细胞内去极化诱发的单一EPSPs均受到抑制,而米勒轴突中动作电位的传导以及运动神经元的逆向动作电位实际上未发生变化。EPSPs的电成分以及化学成分的深度抑制,再加上将所得结果与七鳃鳗网状运动突触结构的现有形态学数据进行比较,得出结论:抑制性突触可能位于运动神经元树突上兴奋性突触的附近。

相似文献

1
[Inhibitory effects of taurine on spinal cord motoneurons of the lamprey].[牛磺酸对七鳃鳗脊髓运动神经元的抑制作用]
Neirofiziologiia. 1987;19(4):551-4.
2
[The effect of glycine and gamma-aminobutyric acid on the evoked activity of the spinal cord motor neurons in the lamprey].[甘氨酸和γ-氨基丁酸对七鳃鳗脊髓运动神经元诱发活动的影响]
Neirofiziologiia. 1990;22(3):391-4.
3
[The effect of glycine and gamma-aminobutyric acid on the excitatory postsynaptic potentials of the spinal motor neurons in the lamprey in the presence of antagonists].[在存在拮抗剂的情况下,甘氨酸和γ-氨基丁酸对七鳃鳗脊髓运动神经元兴奋性突触后电位的影响]
Neirofiziologiia. 1990;22(3):394-7.
4
[Electrotonic excitatory postsynaptic potentials evoked by stimulation of ventral roots in motoneurons and Muller axons of Lampetra fluviatilis lampreys].[通过刺激七鳃鳗运动神经元和米勒轴突的腹根诱发的电紧张性兴奋性突触后电位]
Zh Evol Biokhim Fiziol. 1978 Nov-Dec;14(6):581-8.
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[Effect of penicillin on the synaptic activity of isolated spinal cord motor neurons in the lamprey].[青霉素对七鳃鳗离体脊髓运动神经元突触活动的影响]
Neirofiziologiia. 1992;24(2):151-60.
6
[Synaptic effects induced in lamprey motor neurons by direct stimulation of individual presynaptic fibers].[通过直接刺激单个突触前纤维在七鳃鳗运动神经元中诱导的突触效应]
Neirofiziologiia. 1977;9(4):390-6.
7
[Electrotonic and chemical EPSPs in lamprey motor neurons following stimulation of the descending tract and posterior root afferents].[刺激下行束和后根传入纤维后七鳃鳗运动神经元中的电紧张性和化学性兴奋性突触后电位]
Neirofiziologiia. 1977;9(5):512-7.
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[Interaction between primary segmental afferents and motor neurons in the spinal cord of the lamprey].[七鳃鳗脊髓中初级节段传入神经与运动神经元之间的相互作用]
Fiziol Zh SSSR Im I M Sechenova. 1984 Aug;70(8):1178-88.
9
Efficiency of electrical transmission in reticulomotoneuronal synapses of lamprey spinal cord.七鳃鳗脊髓网状运动神经元突触的电传递效率
Exp Brain Res. 1987;69(1):131-9. doi: 10.1007/BF00247036.
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[Quantitative study of the reticular-motor neuronal contacts in the spinal cord of the lampern].七鳃鳗脊髓中网状运动神经元接触的定量研究
Neirofiziologiia. 1988;20(6):814-7.

引用本文的文献

1
Influence of taurine on the electrically regulated ionic channels of the somatic membrane of neurons of the pond snail.牛磺酸对池塘蜗牛神经元体膜电调控离子通道的影响。
Neurosci Behav Physiol. 1992 Jul-Aug;22(4):315-9. doi: 10.1007/BF01182873.