Batueva I V, Suderevskaia E I
Neirofiziologiia. 1990;22(3):391-4.
The influence of bath application of glycine (10(-5)-10(-3) mol/l) and gamma-aminobutyric acid (10(-5)-10(-2) mol/l) on the monosynaptic EPSPs evoked in motoneurons by stimulation of a descending tract and individual Müller axons was studied in spinal cord-notochord preparation of lamprey (Lampetra fluviatilis). Both amino acids hyperpolarized the motoneuron membrane and depressed the evoked synaptic activity. But the inhibitory effect of glycine was stronger and it was revealed at lower concentrations as compared to that of GABA. It is concluded that glycine is more effective in blocking the postsynaptic motoneuron activity in comparison with GABA in the spinal cord of lamprey.
在七鳃鳗（Lampetra fluviatilis）的脊髓-脊索标本中，研究了浴用甘氨酸（10⁻⁵ - 10⁻³ mol/L）和γ-氨基丁酸（10⁻⁵ - 10⁻² mol/L）对下行传导束和单个米勒氏轴突刺激诱发的运动神经元单突触兴奋性突触后电位（EPSPs）的影响。两种氨基酸均使运动神经元膜超极化并抑制诱发的突触活动。但甘氨酸的抑制作用更强，与γ-氨基丁酸相比，其在更低浓度时即可显现。得出的结论是，在七鳃鳗脊髓中，与γ-氨基丁酸相比，甘氨酸在阻断突触后运动神经元活动方面更有效。
