Melhem Yara, Hussein Al-Janabi Moatasem, Mansour Maha, Suleman Hameed, Al-Shehabi Zuheir
Department of Dermatology, Tishreen University Hospital, Lattakia, Syria.
Department of Pathology, Cancer Research Center, Tishreen University Hospital, Lattakia, Syria.
Ann Med Surg (Lond). 2022 Nov 8;84:104834. doi: 10.1016/j.amsu.2022.104834. eCollection 2022 Dec.
Mycosis Fungoides, the most common type of cutaneous T-cell lymphomas (CTCLs), has typically an indolent course over years or decades. Patches grow into infiltrated plaques which may turn eventually into tumors. The tumor stage represents advanced lymphoma, but this occurs in a minority (∼10%) of cases.
we present a rare case of mycosis fungoides in a 30-year-old woman showing rapid progression to tumor stage, unlike the indolent clinical course seen classically.
Mycosis Fungoides (MF) is the most common primary cutaneous T-cell lymphoma, representing less than 1% of the total number of non-Hodgkin lymphoma. Patients with a classical type of MF progress from patch stage to plaque stage and finally to tumor stage disease, and they have a protracted clinical course over years or even decades.
Although mycosis fungoides is a rare disease, it requires a high degree of suspicion clinically. The disease can have an excellent prognosis when identified and treated promptly.
蕈样肉芽肿是皮肤T细胞淋巴瘤（CTCL）最常见的类型，通常在数年或数十年间呈惰性病程。斑片发展为浸润性斑块，最终可能转变为肿瘤。肿瘤期代表晚期淋巴瘤，但这种情况仅发生在少数（约10%）病例中。
我们报告一例罕见的30岁女性蕈样肉芽肿病例，与典型的惰性临床病程不同，该病例迅速进展至肿瘤期。
蕈样肉芽肿（MF）是最常见的原发性皮肤T细胞淋巴瘤，占非霍奇金淋巴瘤总数的比例不到1%。典型MF患者从斑片期进展至斑块期，最终发展为肿瘤期疾病，其临床病程长达数年甚至数十年。
尽管蕈样肉芽肿是一种罕见疾病，但临床上需要高度怀疑。若能及时识别并治疗，该病可获得良好预后。
