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巨细胞病毒淋巴结炎酷似复发性弥漫性大B细胞淋巴瘤。

Cytomegalovirus lymphadenitis mimicking a relapsed diffuse large B-cell lymphoma.

作者信息

Delaye Matthieu, Ricard Laure, Maisonobe Lucas, Chartier Suzanne, Coppo Paul

机构信息

Service d'Hématologie Clinique et Thérapie Cellulaire, Hôpital Saint-Antoine, AP-HP Sorbonne University Paris France.

Infectious Diseases Department, Hôpital Saint-Antoine Groupe Hospitalier Sorbonne Université, APHP Paris France.

出版信息

Clin Case Rep. 2022 Dec 26;10(12):e6611. doi: 10.1002/ccr3.6611. eCollection 2022 Dec.

DOI:10.1002/ccr3.6611
PMID:36583199
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9792642/
Abstract

Cytomegalovirus (CMV) reactivation is frequent after autologous stem cell transplantation (ASCT), but generalized CMV lymphadenitis is rare. We report a CMV lymphadenitis after an ASCT mimicking a relapse of a diffuse large B-cell lymphoma. After histopathological documentation, CMV lymphadenitis should be treated to avoid systemic progression.

摘要

巨细胞病毒(CMV)再激活在自体干细胞移植(ASCT)后很常见,但全身性CMV淋巴结炎很少见。我们报告了1例ASCT后发生的CMV淋巴结炎,其表现类似弥漫性大B细胞淋巴瘤复发。经组织病理学确诊后,应治疗CMV淋巴结炎以避免病情进展至全身。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d99f/9792642/0eb4c03ac5fa/CCR3-10-e6611-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d99f/9792642/0eb4c03ac5fa/CCR3-10-e6611-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d99f/9792642/0eb4c03ac5fa/CCR3-10-e6611-g001.jpg

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本文引用的文献

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A Clinicopathological Study of Cytomegalovirus Lymphadenitis and Tonsillitis and Their Association with Epstein-Barr Virus.巨细胞病毒淋巴结炎和扁桃体炎的临床病理研究及其与爱泼斯坦-巴尔病毒的关联
Infect Dis Ther. 2021 Dec;10(4):2661-2675. doi: 10.1007/s40121-021-00528-1. Epub 2021 Oct 8.
2
Is Cytomegalovirus Surveillance Necessary for Patients With Low Reactivation Risk in an Autologous Hematopoietic Cell Transplantation Setting?在自体造血细胞移植环境中,对于再激活风险较低的患者,是否有必要进行巨细胞病毒监测?
Transplant Proc. 2017 Oct;49(8):1911-1915. doi: 10.1016/j.transproceed.2017.05.007.
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Cytomegalovirus infection in hematologic malignancy settings other than the allogeneic transplant.
除同种异体移植外的血液系统恶性肿瘤环境中的巨细胞病毒感染
Hematol Oncol. 2018 Apr;36(2):381-391. doi: 10.1002/hon.2453. Epub 2017 Jun 29.
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5
Management of CMV, HHV-6, HHV-7 and Kaposi-sarcoma herpesvirus (HHV-8) infections in patients with hematological malignancies and after SCT.血液系统恶性肿瘤患者及异基因造血干细胞移植后巨细胞病毒、人疱疹病毒6型、人疱疹病毒7型和卡波西肉瘤疱疹病毒(人疱疹病毒8型)感染的管理
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