Department of Medicine, University of California, Irvine, 333 The City Blvd. West, Suite 400, Orange, CA, 92868, USA.
Department of Medicine, Division of Cardiology, University of California, Irvine, USA.
BMC Cardiovasc Disord. 2022 Dec 30;22(1):576. doi: 10.1186/s12872-022-03018-5.
Atrial myxomas account for approximately 50% of all primary cardiac tumors. The size, location, risk of embolic event, and involvement of other cardiac structures, are all factors that contribute to the wide range of presentation for cardiac myxomas. Patients with myxomas may remain asymptomatic, while others may report symptoms such as fatigue and fever, dyspnea, and syncope. It is important to recognize arrhythmias as an uncommon symptom of myxomas.
We report a rare case of a 67-year-old man who presented with pre-syncopal episodes, symptomatic bradycardia, and night sweats found to have a 5.5 × 5.1 × 3 cm myxoma in the left atrium. During diastole the mass caused dynamic flow obstruction across the mitral valve. The patient underwent surgical resection of the mass given his symptomatology and risk of embolic events. Removal of the myxoma resulted in resolution of both pre-syncopal episodes and the patient's sinus bradycardia.
Atrial myxomas are a rare cause of pre-syncope and symptomatic bradycardia. It is important to have a clinical suspicion for atrial myxomas given early diagnosis and surgical intervention are key in improving the prognosis of these patients. This case also highlights the importance of taking into account the source of the myxoma's blood supply in relationship to other cardiac structures, and further correlating these findings with clinical symptoms.
心房黏液瘤约占所有原发性心脏肿瘤的 50%。大小、位置、栓塞事件风险以及其他心脏结构的受累情况,都是导致心脏黏液瘤表现范围广泛的因素。黏液瘤患者可能无症状,而另一些患者可能报告疲劳和发热、呼吸困难和晕厥等症状。认识到心律失常是黏液瘤的一种不常见症状很重要。
我们报告了一例罕见病例,一名 67 岁男性出现晕厥前发作、有症状的心动过缓以及夜间出汗,经检查发现左心房有一个 5.5×5.1×3cm 的黏液瘤。在舒张期,肿块导致二尖瓣上出现动态血流阻塞。鉴于患者的症状和栓塞事件风险,对其进行了肿块切除术。切除黏液瘤后,晕厥前发作和患者的窦性心动过缓均得到缓解。
心房黏液瘤是晕厥前发作和有症状心动过缓的罕见原因。鉴于早期诊断和手术干预对于改善这些患者的预后至关重要,因此临床上应高度怀疑心房黏液瘤。本病例还强调了在考虑黏液瘤的血液供应来源与其他心脏结构的关系时,以及进一步将这些发现与临床症状相关联的重要性。