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新型冠状病毒疾病中的原发性肾上腺功能不全和心肌炎:一例报告。

Primary adrenal insufficiency and myocarditis in COVID-19 disease: a case report.

机构信息

Department of Endocrinology, Rasool Akram Medical Complex, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.

Department of Cardiology, Rasool Akram Medical Complex, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.

出版信息

BMC Endocr Disord. 2022 Dec 31;22(1):336. doi: 10.1186/s12902-022-01257-3.

DOI:10.1186/s12902-022-01257-3
PMID:36587233
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9805346/
Abstract

BACKGROUND

COVID-19 has different manifestations from respiratory to GI problems, and some of them are more common, but some are rare. Reporting rare cases can significantly advance our understanding of the disease.

CASE PRESENTATION

In this case, we report an 18-year-old teenage boy with chest pain and resistant hypotension following COVID-19 infection, finally diagnosed as primary adrenal insufficiency and COVID-19 myocarditis.

CONCLUSION

Adrenal insufficiency can be life-threatening due to its adverse effects on hemodynamic and electrolyte equilibrium. In addition, COVID-19 induced myocarditis can make the situation more complicated.

摘要

背景

COVID-19 的表现形式从呼吸道问题到胃肠道问题各不相同,其中一些较为常见,而有一些则较为罕见。报告罕见病例可极大地促进我们对该疾病的认识。

病例介绍

本例中,我们报告了一例 COVID-19 感染后继发胸痛和难治性低血压的 18 岁青少年,最终诊断为原发性肾上腺功能不全和 COVID-19 心肌炎。

结论

肾上腺功能不全可危及生命,因为它对血流动力学和电解质平衡有不良影响。此外,COVID-19 引起的心肌炎可使病情更为复杂。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb5d/9805676/94fafe557a5d/12902_2022_1257_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb5d/9805676/94fafe557a5d/12902_2022_1257_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb5d/9805676/94fafe557a5d/12902_2022_1257_Fig1_HTML.jpg

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2
Autoimmune complications of COVID-19.新型冠状病毒肺炎的自身免疫并发症
J Med Virol. 2022 Jan;94(1):54-62. doi: 10.1002/jmv.27292. Epub 2021 Aug 31.
3
Delayed-onset myocarditis following COVID-19.新型冠状病毒肺炎(COVID-19)后迟发性心肌炎
Endocr Pathol. 2023 Dec;34(4):406-436. doi: 10.1007/s12022-023-09771-3. Epub 2023 May 20.
Lancet Respir Med. 2021 Apr;9(4):e32-e34. doi: 10.1016/S2213-2600(21)00085-0. Epub 2021 Feb 19.
4
The Adrenal Cortex, an Underestimated Site of SARS-CoV-2 Infection.肾上腺皮质,被低估的 SARS-CoV-2 感染部位。
Front Endocrinol (Lausanne). 2021 Jan 8;11:593179. doi: 10.3389/fendo.2020.593179. eCollection 2020.
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New onset adrenal insufficiency in a patient with COVID-19.COVID-19 患者新发肾上腺皮质功能不全。
BMJ Case Rep. 2021 Jan 18;14(1):e237690. doi: 10.1136/bcr-2020-237690.
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From ACE2 to COVID-19: A multiorgan endothelial disease.从血管紧张素转换酶2到2019冠状病毒病:一种多器官内皮疾病
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