COVID-19 患者新发肾上腺皮质功能不全。
New onset adrenal insufficiency in a patient with COVID-19.
机构信息
Internal Medicine, Sheikh Khalifa Medical City, Abu Dhabi, UAE.
Internal Medicine, Sheikh Khalifa Medical City, Abu Dhabi, UAE
出版信息
BMJ Case Rep. 2021 Jan 18;14(1):e237690. doi: 10.1136/bcr-2020-237690.
Abstract
SARS-CoV-2 is the cause of COVID-19. Since the outbreak and rapid spread of COVID-19, it has been apparent that the disease is having multi-organ system involvement. Still its effect in the endocrine system is not fully clear and data on cortisol dynamics in patients with COVID-19 are not yet available. SARS-CoV-2 can knock down the host's cortisol stress response. Here we present a case of a 51-year-old man vomiting for 10 days after having confirmed COVID-19 infection. He had hypotension and significant hyponatraemia. Work-up was done including adrenocorticotropic hormone stimulation test. He was diagnosed as suffering from adrenal insufficiency and started on steroids with subsequent improvement in both blood pressure and sodium level. COVID-19 can cause adrenal insufficiency. Clinicians must be vigilant about the possibility of an underlying relative cortisol deficiency in patients with COVID-19.
摘要
SARS-CoV-2 是 COVID-19 的病因。自 COVID-19 的爆发和迅速传播以来，很明显这种疾病涉及多器官系统。然而，其在内分泌系统中的作用尚不完全清楚，COVID-19 患者的皮质醇动态数据尚不可用。SARS-CoV-2 可以削弱宿主的皮质醇应激反应。在这里，我们报告了一例 51 岁男性，在确诊 COVID-19 感染后 10 天开始呕吐。他出现低血压和严重低钠血症。进行了包括促肾上腺皮质激素刺激试验在内的检查。他被诊断为肾上腺功能不全，并开始使用类固醇治疗，随后血压和钠水平均有所改善。COVID-19 可导致肾上腺功能不全。临床医生必须警惕 COVID-19 患者潜在的相对皮质醇缺乏的可能性。
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