Alpini D, Corgiolu E, Pozzi P L, Corti A
Divisione ORL, Ospedale Busto Arsizio (VA), Italia.
Pediatr Med Chir. 1987 Mar-Apr;9(2):155-7.
Authors studied 42 children affected with obstructive rhinopathy. They complained nose obstruction with mono or bilateral difficult nasal breathing, permanent (rarely seasonal) symptoms, hypertrophic adenoids, nasal hypersecretion, hearing loss and recurrent otitis media. Two groups of tests were performed: 1) to document the entity of nasal stenosis and the correlated otologic diseases: rhinomanometry by Mercury NR1 rhinomanometer; tympanogram, classified according to Jerger; tubotympanogram, according to Honjo, Morimitsu and Cocchini. 2) To formulate etiologic hypothesis: Prick skin tests; immunoenzymatic specific and total IgE assay; nasal smear; secretory IgA assay. In 8 children anamnesis showed an environmental allergy while familiar anamnesis was positive in 26 cases. Skin tests and/or IgE assay were positive in 14. Neutrophilia in nasal smear was noted in 30, lymphocytosis in 2 and eosinophilia in 5. Secretory IgA were decreased in 39. Children were divided into three classes: A: no documented atopic component; B: disergic children; C: allergic children.
作者对42名患有阻塞性鼻病的儿童进行了研究。他们主诉有鼻塞，伴有单侧或双侧鼻腔呼吸困难、持续性（很少有季节性）症状、腺样体肥大、鼻部分泌物过多、听力损失和复发性中耳炎。进行了两组测试：1）记录鼻腔狭窄的情况以及相关的耳科疾病：使用水银NR1鼻阻力计进行鼻阻力测量；根据耶尔格分类法进行鼓室图检查；根据本庄、森光和科基尼分类法进行咽鼓管鼓室图检查。2）提出病因假设：皮肤点刺试验；免疫酶法检测特异性和总IgE；鼻涂片检查；分泌型IgA检测。在8名儿童中，个人史显示有环境过敏，而家族史在26例中呈阳性。皮肤试验和/或IgE检测在14例中呈阳性。鼻涂片中30例有中性粒细胞增多，2例有淋巴细胞增多，5例有嗜酸性粒细胞增多。39例分泌型IgA降低。儿童被分为三类：A类：无记录的特应性成分；B类：反应性儿童；C类：过敏性儿童。
