Angrisano A, Di Berardino L, Montrasio G, Compostella G
Divisione di Pediatria, Presidio ospedaliero di Bollate, Italia.
Pediatr Med Chir. 1987 Mar-Apr;9(2):159-60.
For many years molds have considered to be important causes of rhinitis and asthma but since they have been poorly studied many questions remain unanswered. Allergological and epidemiological considerations have been made by the authors concerning the role of the Alternaria tenuis in respiratory diseases in children. 253 subjects were skin tested, 9.48 percent had an immediate reaction, 3.55 were also positive to the fungus only. Good correlation was observed between positive skin tests and RAST (66%). This study confirmed that probably Alternaria tenuis has an important role as immunopathogen for rhinitis and asthma in children. The authors discuss epidemiological considerations and related problems.
多年来，霉菌一直被认为是鼻炎和哮喘的重要病因，但由于对其研究不足，许多问题仍未得到解答。作者从变态反应学和流行病学角度对细交链孢霉在儿童呼吸道疾病中的作用进行了研究。对253名受试者进行了皮肤试验，9.48%的人有即刻反应，3.55%仅对该真菌呈阳性反应。皮肤试验阳性与放射变应原吸附试验（RAST）之间存在良好的相关性（66%）。该研究证实，细交链孢霉可能作为儿童鼻炎和哮喘的免疫病原体发挥重要作用。作者讨论了流行病学方面的考虑因素及相关问题。
