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治疗过敏性眼病的实践模式和观点:印度眼科医生的调查。

Practice patterns and opinions in the treatment of allergic eye disease: A survey among Indian ophthalmologists.

机构信息

Cornea and Anterior Segment Service, L.V Prasad Eye Institute, Patia, Bhubaneswar, Odisha, India.

出版信息

Indian J Ophthalmol. 2023 Jan;71(1):80-85. doi: 10.4103/ijo.IJO_1360_22.

Abstract

PURPOSE

Management of allergic eye disease is seldom straightforward and often challenging. We conducted an online survey to elicit opinions on the preferred practice pattern in the treatment of allergic eye disease.

METHODS

An online survey questionnaire was sent to all practicing ophthalmologists using social media platforms. The respondents were asked about their clinical experience and preferred treatment in various scenarios such as mild-moderate vernal keratoconjunctivitis (VKC), chronic VKC, refractory VKC, steroid responders, giant papillae, and shield ulcer. Respondents were asked about the newer molecule (alcaftadine) and reservations regarding systemic immuno-suppressants and ordering allergy tests in their practice.

RESULTS

Ninety - one participants responded to the survey. About 57.1% of ophthalmologists reported coming across more than 10 cases per week in their practice. The most common age group was 5-10 years (61.1%), but adult onset VKC was also reported at 41.6% (1-2 per month), 37.1% (3-5 per month), and 13.5% (more than 10 per month). The disease is perennially present (36.7%), and a mixed form has been reported by 47.8% of ophthalmologists. Dual-acting agents were preferred by 40% in mild-moderate clinical variants. Topical steroids in slow tapering dosage were preferred by 86.7% in their prescription. Tacrolimus 0.03% was preferred by 65.9% and given for at least 3 months of continuous usage by 47.6% of ophthalmologists. High-dose topical steroids were preferred for giant papillae (67.8%) and Shields ulcers (68.3%) in our survey. Supratarsal steroid injection was preferred by 50% in treating refractory VKC in our survey.

CONCLUSION

Allergic eye disease is a common yet annoying disease. The signs and symptoms can vary from subtle, innocuous forms to devastating variants affecting vision and day-to-day work. This survey aims to elicit responses from clinicians spreading across different geographical areas and compares responses based on experience in practice.

摘要

目的

过敏性眼病的管理并不总是简单直接的,而且往往具有挑战性。我们进行了一项在线调查,以了解关于过敏性眼病治疗的首选实践模式的意见。

方法

使用社交媒体平台向所有执业眼科医生发送在线调查问卷调查。受访者被问及他们在各种情况下的临床经验和首选治疗方法,例如轻度中度春季角结膜炎(VKC)、慢性 VKC、难治性 VKC、类固醇反应者、巨大乳头和盾状溃疡。受访者被问及新型分子(alcaftadine)以及他们在实践中对全身免疫抑制剂和过敏测试的保留意见。

结果

91 名参与者对调查做出了回应。大约 57.1%的眼科医生报告说,在他们的实践中每周遇到超过 10 例病例。最常见的年龄组是 5-10 岁(61.1%),但也有 41.6%(每月 1-2 例)、37.1%(每月 3-5 例)和 13.5%(每月超过 10 例)的成年发病 VKC。这种疾病常年存在(36.7%),47.8%的眼科医生报告说存在混合形式。在轻度中度临床变异中,40%的人更喜欢双作用药物。86.7%的受访者在处方中首选缓慢减量的局部类固醇。65.9%的人更喜欢他克莫司 0.03%,47.6%的人至少连续使用 3 个月。在我们的调查中,高剂量局部类固醇被认为是巨大乳头(67.8%)和盾状溃疡(68.3%)的首选。50%的人在治疗难治性 VKC 时更喜欢行上睑皮下类固醇注射。

结论

过敏性眼病是一种常见但令人烦恼的疾病。症状和体征可以从轻微、无害的形式到影响视力和日常工作的严重形式不等。这项调查旨在从分布在不同地理区域的临床医生那里获得反馈,并根据实践经验进行比较。

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本文引用的文献

2
Vernal Keratoconjunctivitis.
Surv Ophthalmol. 2019 May-Jun;64(3):289-311. doi: 10.1016/j.survophthal.2018.12.001. Epub 2018 Dec 12.
3
Omalizumab in Severe Refractory Vernal Keratoconjunctivitis in Children: Case Series and Review of the Literature.
Ophthalmol Ther. 2017 Jun;6(1):195-206. doi: 10.1007/s40123-016-0074-2. Epub 2016 Dec 1.
4
Tacrolimus in Corticosteroid-Refractory Vernal Keratoconjunctivitis.
Cornea. 2016 Nov;35(11):1444-1448. doi: 10.1097/ICO.0000000000000918.
5
Efficacy and safety of low-dose topical tacrolimus in vernal keratoconjunctivitis.
Clin Ophthalmol. 2016 Apr 7;10:643-7. doi: 10.2147/OPTH.S99157. eCollection 2016.
7
Omalizumab Treatment of Vernal Keratoconjunctivitis.
JAMA Ophthalmol. 2016 Apr;134(4):461-3. doi: 10.1001/jamaophthalmol.2015.5679.
8
Efficacy and safety of topical cyclosporine A 0.05% in vernal keratoconjunctivitis.
Singapore Med J. 2016 Sep;57(9):507-10. doi: 10.11622/smedj.2015161. Epub 2015 Nov 13.
10
Demographic and clinical profile of vernal keratoconjunctivitis at a tertiary eye care center in India.
Indian J Ophthalmol. 2013 Sep;61(9):486-9. doi: 10.4103/0301-4738.119431.

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