印度一家三级眼科保健中心的春季角结膜炎的人口统计学和临床特征。
Demographic and clinical profile of vernal keratoconjunctivitis at a tertiary eye care center in India.
机构信息
Corneal and Anterior Segment Service, L V Prasad Eye Institute, Kallam Anji Reddy Campus, Hyderabad, Andhra Pradesh, India.
出版信息
Indian J Ophthalmol. 2013 Sep;61(9):486-9. doi: 10.4103/0301-4738.119431.
PURPOSE
To study the demographic and clinical profile of patients with vernal keratoconjunctivitis (VKC) at a tertiary eye care center in India.
MATERIALS AND METHODS
Retrospective chart analysis of 468 patients of VKC seen from January 2006 to December 2006.
RESULTS
Mean age at presentation was 12 years. Majority of the patients had mixed pattern disease (72%). Chronic perennial disease was seen in 36% patients. Personal or family history of allergies was noted in 5% patients. Severe disease based on clinical grading was present in 37% patients. Moderate to severe vision loss was seen in 12% of total population. Persistent disease beyond 20 years of age was found in 12% patients. VKC-related complications such as corneal scarring (11%), shield ulcer (3%), keratoconus (6%), and limbal stem cell deficiency (1.2%) were seen. Treatment-related complications like corticosteroid-induced cataract and glaucoma were seen in 6% and 4% of patients, respectively.
CONCLUSION
Clinical pattern of VKC seen in the tropical climate of India is essentially similar to that seen in other tropical countries. Few distinct features that we noted represent chronic perennial disease, low association with atopy, and higher propensity for disease and treatment-related complications.
目的
研究印度一家三级眼科中心的春季角结膜炎（VKC）患者的人口统计学和临床特征。
材料和方法
对 2006 年 1 月至 2006 年 12 月期间就诊的 468 例 VKC 患者的病历进行回顾性分析。
结果
就诊时的平均年龄为 12 岁。大多数患者为混合性疾病（72%）。36%的患者患有慢性常年性疾病。5%的患者有过敏的个人或家族史。根据临床分级，37%的患者病情严重。12%的总人群视力中度至重度下降。12%的患者发现疾病持续时间超过 20 年。VKC 相关并发症，如角膜瘢痕（11%）、盾状溃疡（3%）、圆锥角膜（6%）和角膜缘干细胞缺乏症（1.2%）。分别有 6%和 4%的患者出现与治疗相关的并发症，如皮质类固醇诱导的白内障和青光眼。
结论
印度热带气候中观察到的 VKC 临床模式与其他热带国家基本相似。我们注意到一些明显的特征，代表慢性常年性疾病、与特应性的低关联，以及更高的疾病和治疗相关并发症倾向。
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