角化棘皮瘤治疗管理的最新综述
An Updated Review of the Therapeutic Management of Keratoacanthomas.
作者信息
Ambur Austin, Clark Abigale, Nathoo Rajiv
机构信息
All authors are with the Department of Dermatology at KCU-GME Advanced Dermatology and Cosmetic Surgery in Oviedo, Florida.
出版信息
J Clin Aesthet Dermatol. 2022 Dec;15(12 Suppl 1):S16-S22.
OBJECTIVE
Keratoacanthomas are fast-growing cutaneous neoplasms that can be difficult to distinguish from squamous cell carcinoma, both clinically and histologically. The uncertain behavior of these neoplasms creates a challenge in management, and treatment choice often varies significantly between cases. The objective of this review is to discuss the most common and up-to-date treatment modalities used in the management of keratoacanthomas.
METHODS
A literature search was performed using PubMed to access and review relevant keratoacanthoma treatment modalities published within the last 40 years. Keywords searched included "keratoacanthoma," "Grzybowski syndrome," "Ferguson-Smith syndrome," "Witten-Zac syndrome," and "Muir-Torre" syndrome.
RESULTS
Our search resulted in 3,408 articles, of which 67 articles were ultimately included in this review.
CONCLUSION
Although surgical removal with excision or Mohs micrographic surgery remains the standard of therapy, there are many alternative therapeutic modalities that can be utilized.
目的
角化棘皮瘤是一种生长迅速的皮肤肿瘤，在临床和组织学上都很难与鳞状细胞癌区分开来。这些肿瘤的行为不确定给治疗带来了挑战，而且不同病例的治疗选择往往差异很大。本综述的目的是讨论角化棘皮瘤治疗中最常用和最新的治疗方式。
方法
使用PubMed进行文献检索，以获取和回顾过去40年内发表的有关角化棘皮瘤治疗方式的相关文献。检索的关键词包括“角化棘皮瘤”“格日博夫斯基综合征”“弗格森-史密斯综合征”“维滕-扎克综合征”和“穆尔-托里”综合征。
结果
我们的检索得到3408篇文章，其中67篇最终纳入本综述。
结论
尽管手术切除或莫氏显微外科手术仍然是治疗的标准方法，但还有许多其他治疗方式可供使用。
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