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导管消融术中的性别和种族差异。

Sex and racial disparities in catheter ablation.

作者信息

Vandenberk Bert, Chew Derek S, Parkash Ratika, Gillis Anne M

机构信息

Department of Cardiac Sciences, Libin Cardiovascular Institute, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.

Department of Cardiovascular Sciences, University of Leuven, Leuven, Belgium.

出版信息

Heart Rhythm O2. 2022 Dec 16;3(6Part B):771-782. doi: 10.1016/j.hroo.2022.08.002. eCollection 2022 Dec.

Abstract

Sex and racial disparities in the presentation, diagnosis, and management of cardiac arrhythmias are recognized. Sex-specific differences in electrophysiological parameters are well known and are predominantly related to differences in ion channel expression and the influence of sex hormones. However, the relationship between hormonal or racial influence and arrhythmia mechanisms, presentation, and management needs to be better defined. Women and racial and ethnic groups are less likely to undergo catheter ablation procedures for treatment of cardiac arrhythmias. Underrepresentation of women and racial/ethnic groups in clinical trials has resulted in significant knowledge gaps. Whether sex and racial disparities in arrhythmia management reflect barriers in access to care, physician bias, patient values, and preferences or other factors requires further study.

摘要

心律失常在表现、诊断和管理方面的性别及种族差异已得到公认。电生理参数的性别特异性差异众所周知,且主要与离子通道表达的差异以及性激素的影响有关。然而,激素或种族影响与心律失常机制、表现及管理之间的关系仍需进一步明确。女性以及种族和族裔群体接受心律失常导管消融治疗的可能性较小。临床试验中女性和种族/族裔群体的代表性不足导致了重大的知识空白。心律失常管理中的性别和种族差异是否反映了获得医疗服务的障碍、医生偏见、患者价值观和偏好或其他因素,仍需进一步研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ca6/9795271/92eb77632ec8/gr1.jpg

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