[Role of gamma-aminobutyric acid in activating the hypophyseo-testicular complex in male mice in the presence of females].

Experiments on male mice of 3 inbred strains (CBA/Lac, A/He, and BALB) have shown that an increase in the level of testosterone in the peripheral blood induced by the presence of a recipient female mouse, is blocked under the conditions of gamma-aminobutyric acid (GABA) accumulation in the body. A GABA inhibitory effect depends on a genotype. Neither the blockade of receptors to GABA, nor a decrease in its content have produced any effect on an increase in the blood level of testosterone in sexual excitement. It has been assumed that the GABAergic mechanism inhibits sexual excitement of a male mouse during its meeting with a recipient female mouse under stress conditions only.