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对[未明确的s和某个对象]之间相互作用的深入了解为对抗鱼虱病提供了未来的治疗策略。

An insight into the interaction between s and offers future therapeutic strategy to combat argulosis.

作者信息

Thakur Kushal, Sharma Ankita, Sharma Dixit, Brar Bhavna, Choudhary Kanika, Sharma Amit Kumar, Mahajan Danish, Kumar Ranjit, Kumar Sunil, Kumar Rakesh

机构信息

Department of Animal Science, School of Life Sciences, Central University of Himachal Pradesh, Dharamshala, Himachal Pradesh 176206 India.

Centre for Computational Biology and Bioinformatics, School of Life Sciences, Central University of Himachal Pradesh, Dharamshala, Himachal Pradesh 176206 India.

出版信息

Aquac Int. 2023;31(3):1607-1621. doi: 10.1007/s10499-022-01043-x. Epub 2022 Dec 27.

Abstract

Aquaculture and fisheries are salient flourishing sectors in the world but their sustainability is often afflicted by several pathogenic diseases. Among all the pathogenic diseases of fish, parasitic diseases are found to be a major cause of concern. Argulosis is one of the dominant parasitic problems encountered in Indian aquaculture practices. s is the most prevalent argulid species harming the Indian major carp species including The major carps respond to parasitic infestation by elevating various immune relevant genes. The therapeutic chemicals, synthetic drugs and other plant extracts have made a progress in the fight against argulosis. However, there is no effective vaccine and drugs are available for this disease. Thus, designing efficient, cost-effective and eco-friendly control and treatment strategies for argulosis is presently needed. Keeping the aforementioned facts in mind, the current review elaborated the immunological interaction between and , available combat tactics, highlighted the already identified vaccine candidates to design effective control measures and illustrated the use of omics technology in future to combat argulosis.

摘要

水产养殖和渔业是全球蓬勃发展的重要领域,但其可持续性常常受到多种致病疾病的困扰。在鱼类的所有致病疾病中,寄生虫病被认为是一个主要的关注点。锚头鳋病是印度水产养殖实践中遇到的主要寄生虫问题之一。 是危害印度主要鲤科鱼类(包括 )的最普遍的锚头鳋物种。主要鲤科鱼类通过提高各种免疫相关基因来应对寄生虫感染。治疗化学品、合成药物和其他植物提取物在对抗锚头鳋病方面取得了进展。然而,目前尚无针对该疾病的有效疫苗,且药物也有限。因此,目前需要设计出高效、经济且环保的锚头鳋病防控和治疗策略。鉴于上述事实,本综述阐述了 和 之间的免疫相互作用、现有的应对策略,强调了已确定的疫苗候选物以设计有效的控制措施,并说明了未来利用组学技术对抗锚头鳋病的情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa8d/9792311/9d7c773e4cd3/10499_2022_1043_Fig1_HTML.jpg

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