Abdelaziz Mohammed, Thorley Daniel, Ahmed Waseem
ENT Department, Tameside General Hospital, Ashton Under Lyne, UK.
J Surg Case Rep. 2022 Dec 28;2022(12):rjac589. doi: 10.1093/jscr/rjac589. eCollection 2022 Dec.
Pancreatic cancer typically presents with a cholestatic picture of jaundice, bloating and bowel changes, secondary to the obstruction of the biliary system. In tail of pancreas metastases, this clinical presentation may be absent, meaning that the disease progression can be more insidious. Cutaneous spread in pancreatic malignancies is often iatrogenic due to direct spread from the tumour site during diagnostic sampling or surgery. Rarely, cutaneous spread can be noted at distant sites, which is associated with widespread disease dissemination and poor prognostic outcomes. Our case focusses on a patient who developed metastatic spread to the chin, as a first presentation, with no other significant associated symptoms identified.
胰腺癌通常表现为胆汁淤积性黄疸、腹胀和肠道改变,继发于胆道系统梗阻。在胰腺尾部转移时,这种临床表现可能不存在,这意味着疾病进展可能更隐匿。胰腺恶性肿瘤的皮肤转移通常是医源性的,因为在诊断性采样或手术期间肿瘤部位直接蔓延所致。很少见的是,皮肤转移可出现在远处部位,这与广泛的疾病播散和不良预后相关。我们的病例聚焦于一名患者,其首次表现为下巴出现转移性扩散,未发现其他明显相关症状。