Maruyama Hitoshi, Tobari Maki, Nagamatsu Hiroaki, Shiina Suichiro, Yamaguchi Tadashi
Department of Gastroenterology, Juntendo University, Tokyo, Japan.
Center for Frontier Medical Engineering, Chiba University, Chiba, Japan.
Front Med (Lausanne). 2022 Dec 14;9:1057045. doi: 10.3389/fmed.2022.1057045. eCollection 2022.
Portal hypertension is a major pathophysiological condition in patients with cirrhosis. This accounts for the occurrence and severity of the various manifestations. The degree is determined by the portal pressure or hepatic venous pressure gradients, both of which are obtained by invasive interventional radiological procedures. Ultrasound (US) is a simple and minimally invasive imaging modality for the diagnosis of liver diseases. Owing to the availability of microbubble-based contrast agents and the development of imaging modes corresponding to contrast effects, contrast-enhanced US (CEUS) has become popular worldwide for the detailed evaluation of hepatic hemodynamics, diffuse liver disease, and focal hepatic lesions. Recent advancements in digital technology have enabled contrast-based demonstrations with improved resolution, leading to a wider range of applications. This review article describes the current role, benefits, and limitations of CEUS in the management of portal hypertension.
门静脉高压是肝硬化患者的一种主要病理生理状态。这解释了各种临床表现的发生及严重程度。其程度由门静脉压力或肝静脉压力梯度决定，这两者均通过侵入性介入放射学检查获得。超声（US）是一种用于诊断肝脏疾病的简单且微创的成像方式。由于基于微泡的造影剂的可用性以及与造影剂效应相对应的成像模式的发展，超声造影（CEUS）在全球范围内已广泛用于详细评估肝脏血流动力学、弥漫性肝病和肝脏局灶性病变。数字技术的最新进展使得基于造影剂的演示具有更高的分辨率，从而导致了更广泛的应用。这篇综述文章描述了CEUS在门静脉高压管理中的当前作用、益处和局限性。
