Seabold J E, Conrad G R, Ponto J A, Kimball D A, Frey E E, Ahmed F, Coughlan J D, Jensen K C
Department of Radiology, University of Iowa Hospitals, Iowa City 52242.
Radiology. 1987 Nov;165(2):355-60. doi: 10.1148/radiology.165.2.3659356.
Thirty-one nonheparinized patients with suspected deep venous thrombophlebitis (DVT) underwent contrast venography and indium-111 platelet scintigraphy (In-111 PS). Venography permitted identification of acute DVT in 12 of 31 cases (39%). One additional patient was considered to have acute DVT despite nonconclusive venography results. In-111 PS results were positive at 4 hours in nine of 13 cases (69%) and at 24 hours in 12 of 13 cases (92%). Two of four patients with false-negative 4-hour In-111 PS studies had received warfarin. Thus, the sensitivity of 4-hour In-111 PS in patients not receiving anticoagulants was 82%. Venography results were negative for acute DVT in 18 cases, and 4-hour In-111 PS studies were negative or equivocal in each. In-111 PS is an alternative to contrast venography for detecting acute DVT. If 4-hour In-111 PS results are positive, anticoagulation can be initiated. Delayed images are necessary if the 4-hour images are negative or equivocal.
31例疑似深静脉血栓性静脉炎（DVT）的未使用肝素治疗的患者接受了静脉造影和铟111血小板闪烁扫描（In - 111 PS）。静脉造影在31例中有12例（39%）确诊为急性DVT。另有1例患者尽管静脉造影结果不明确，但仍被认为患有急性DVT。13例患者中9例（69%）在4小时时In - 111 PS结果呈阳性，13例中有12例（92%）在24小时时呈阳性。4小时In - 111 PS检查结果为假阴性的4例患者中有2例曾接受华法林治疗。因此，未接受抗凝治疗患者中4小时In - 111 PS的敏感性为82%。18例患者静脉造影结果显示急性DVT为阴性，且每例患者4小时In - 111 PS检查结果均为阴性或不明确。In - 111 PS是检测急性DVT的一种替代静脉造影的方法。如果4小时In - 111 PS结果呈阳性，可开始抗凝治疗。如果4小时图像为阴性或不明确，则需要延迟图像。
