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慢性脊髓损伤患者深静脉血栓形成的患病率

Prevalence of deep venous thrombosis in patients with chronic spinal cord injury.

作者信息

Kim S W, Charallel J T, Park K W, Bauerle L C, Shang C C, Gordon S K, Bauman W A

机构信息

Spinal Cord Injury Service, Veterans Affairs Medical Center, Bronx, NY 10468.

出版信息

Arch Phys Med Rehabil. 1994 Sep;75(9):965-8.

PMID:8085931
Abstract

From a group of 229 patients with chronic spinal cord injury (SCI) who were admitted to an SCI Service of a Veterans Affairs Medical Center, a prospective study was performed to determine the prevalence of deep venous thrombosis (DVT) using radionuclide venography on 43 patients in whom this diagnosis was entertained by clinical examination. By physical examination of the total population of 229 patients on admission, patients were selected and then divided into two groups: the clinically DVT-free group (22 patients) and the clinically DVT-suspected group (21 patients). In the clinically DVT-free group, two cases of chronic DVT (9.1%) were detected incidentally. In the clinically DVT-suspected group, 2 cases of chronic DVT (9.5%) and 4 cases of acute DVT (19.0%) were found. In one subject in the DVT-free group, a false positive radionuclide study was suspected and proven by contrast venography. In the 43 patients studied by radionuclide venography, the prevalence of acute DVTs was 9.3% and chronic DVTs, 9.3% (7.0% "true" chronic DVTs). No subjects in the clinically DVT-free group had an acute DVT. Five of 8 DVTs (62.5%) were detected greater than 6 years after SCI and 3 of 4 (75%) of the acute DVTs developed 17 to 33 years after SCI. Thus, the prevalence of acute DVT cases in this chronically immobilized cohort was found to be relatively low when compared with that in prior reports in those with acute SCI, but the prevalence rate of acute DVT cases in the study herein is similar to or lower than that found in the surgical or medical nonambulatory, non-SCI population.

摘要

在一家退伍军人事务医疗中心的脊髓损伤科收治的229例慢性脊髓损伤(SCI)患者中,进行了一项前瞻性研究,以确定对43例临床检查怀疑有深静脉血栓形成(DVT)的患者采用放射性核素静脉造影术检测DVT的患病率。通过对入院时229例患者的总体进行体格检查,选择患者并将其分为两组:临床无DVT组(22例)和临床怀疑有DVT组(21例)。在临床无DVT组中,偶然发现2例慢性DVT(9.1%)。在临床怀疑有DVT组中,发现2例慢性DVT(9.5%)和4例急性DVT(19.0%)。在无DVT组的1名受试者中,怀疑放射性核素检查出现假阳性,并经静脉造影证实。在通过放射性核素静脉造影术研究的43例患者中,急性DVT的患病率为9.3%,慢性DVT的患病率为9.3%(“真正的”慢性DVT为7.0%)。临床无DVT组中没有受试者发生急性DVT。8例DVT中有5例(62.5%)在SCI后6年以上被检测到,4例急性DVT中有3例(75%)在SCI后17至33年发生。因此,与急性SCI患者的先前报告相比,该长期固定队列中急性DVT病例的患病率相对较低,但本研究中急性DVT病例的患病率与手术或内科非卧床、无SCI人群中发现的患病率相似或更低。

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