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心房颤动消融术后复发性肺炎:不要忘记寻找肺静脉狭窄。

Recurrent pneumonia post atrial fibrillation ablation: do not forget to look for pulmonary vein stenosis.

机构信息

Department of Cardiology, Geneva University Hospital, Geneva, Switzerland

Department of Cardiology, Geneva University Hospital, Geneva, Switzerland.

出版信息

BMJ Case Rep. 2022 Dec 7;15(12):e250896. doi: 10.1136/bcr-2022-250896.

DOI:10.1136/bcr-2022-250896
PMID:36593603
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9730375/
Abstract

A man in his 50s presented with persistent chest pain, haemoptysis, cough and dyspnoea 5 months after undergoing catheter ablation for atrial fibrillation (AF). Several chest CT scans suggested pneumonia. Despite adequate treatment for recurrent pneumonia, symptoms persisted. While reviewing the initial chest CT, a partial venous infarction of the left lower lobe associated with severe left inferior pulmonary vein stenosis (PVS) was diagnosed. Stenting of the left inferior pulmonary vein with a vascular bare metal stent was performed, guided by fluoroscopy and transoesophageal echocardiography. Dual antiplatelet therapy (aspirin/clopidogrel) was introduced for 3 months, followed by long-term aspirin monotherapy. The treatment resulted in relief of his symptoms and the resolution of pulmonary opacities on chest CT. Despite low frequency, AF ablation remains the most common cause of acquired PVS. As highlighted in this case, symptoms are not specific and include recurrent pulmonary infection with delayed management.

摘要

一名 50 多岁男性在接受心房颤动 (AF) 的导管消融术后 5 个月时出现持续性胸痛、咯血、咳嗽和呼吸困难。多次胸部 CT 扫描提示肺炎。尽管反复肺炎的治疗充分,但症状仍持续存在。在回顾最初的胸部 CT 时,诊断为左肺下叶部分静脉梗死,伴严重左下肺静脉狭窄 (PVS)。在透视和经食管超声心动图的引导下,对左下肺静脉进行血管裸金属支架置入术。引入双联抗血小板治疗(阿司匹林/氯吡格雷)3 个月,随后长期单独使用阿司匹林。治疗后患者症状缓解,胸部 CT 上肺部混浊度消失。尽管频率较低,但 AF 消融仍然是获得性 PVS 的最常见原因。正如本例所示,症状不具特异性,包括反复肺部感染伴延迟治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/38ff/9730375/c342f6cc7d97/bcr-2022-250896f04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/38ff/9730375/c1932a777854/bcr-2022-250896f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/38ff/9730375/b0fce1471089/bcr-2022-250896f02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/38ff/9730375/2b48914d9fb1/bcr-2022-250896f03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/38ff/9730375/c342f6cc7d97/bcr-2022-250896f04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/38ff/9730375/c1932a777854/bcr-2022-250896f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/38ff/9730375/b0fce1471089/bcr-2022-250896f02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/38ff/9730375/2b48914d9fb1/bcr-2022-250896f03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/38ff/9730375/c342f6cc7d97/bcr-2022-250896f04.jpg

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本文引用的文献

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JACC Clin Electrophysiol. 2017 Jun;3(6):589-598. doi: 10.1016/j.jacep.2017.02.003. Epub 2017 Apr 26.
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Balloon angioplasty versus stenting for pulmonary vein stenosis after pulmonary vein isolation for atrial fibrillation: A meta-analysis.球囊血管成形术与支架置入术治疗心房颤动肺静脉隔离后肺静脉狭窄:荟萃分析。
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2017 HRS/EHRA/ECAS/APHRS/SOLAECE expert consensus statement on catheter and surgical ablation of atrial fibrillation.
2017年心房颤动导管消融与外科消融治疗专家共识声明(由心律学会、欧洲心律协会、欧洲心血管病预防与康复协会、亚太心律学会、拉丁美洲心脏节律学会联合发布)
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Severe Pulmonary Vein Stenosis Resulting From Ablation for Atrial Fibrillation: Presentation, Management, and Clinical Outcomes.严重肺静脉狭窄导致的心房颤动消融:表现、处理和临床结局。
Circulation. 2016 Dec 6;134(23):1812-1821. doi: 10.1161/CIRCULATIONAHA.116.021949. Epub 2016 Oct 28.
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Pulmonary vein stenosis: Etiology, diagnosis and management.肺静脉狭窄:病因、诊断与治疗
World J Cardiol. 2016 Jan 26;8(1):81-8. doi: 10.4330/wjc.v8.i1.81.
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The incidence, diagnosis, and management of pulmonary vein stenosis as a complication of atrial fibrillation ablation.作为心房颤动消融并发症的肺静脉狭窄的发生率、诊断及处理
J Interv Card Electrophysiol. 2014 Jun;40(1):63-74. doi: 10.1007/s10840-014-9885-z. Epub 2014 Mar 14.
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Circ Arrhythm Electrophysiol. 2010 Feb;3(1):32-8. doi: 10.1161/CIRCEP.109.859116. Epub 2009 Dec 7.
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Comparison of stent versus balloon angioplasty for pulmonary vein stenosis complicating pulmonary vein isolation.支架与球囊血管成形术治疗肺静脉隔离术后并发肺静脉狭窄的比较
J Cardiovasc Electrophysiol. 2008 Jul;19(7):673-8. doi: 10.1111/j.1540-8167.2008.01110.x. Epub 2008 Feb 13.