Hanna Sebastian, Palmadottir Vala, Penar Paul L, Boyd James T
University of Vermont Larner College of Medicine, United States.
Landspitali University Hospital, Iceland.
Clin Park Relat Disord. 2022 Dec 17;8:100175. doi: 10.1016/j.prdoa.2022.100175. eCollection 2023.
Neuropsychiatric adverse events have been previously reported following deep brain stimulation (DBS) for Parkinson's disease (PD). Most cases described have involved DBS of the subthalamic nucleus (STN). We report a unique case of acute-onset and reversible psychosis, suicidality, and depressive symptoms following DBS of the globus pallidus internus (GPi) and review the relevant literature.
先前已有报道称,帕金森病(PD)患者在接受脑深部电刺激(DBS)后会出现神经精神不良事件。所描述的大多数病例都涉及丘脑底核(STN)的DBS。我们报告了一例独特的病例,该患者在接受内侧苍白球(GPi)的DBS后出现急性发作且可逆的精神病性症状、自杀观念和抑郁症状,并对相关文献进行了综述。