胎羊肠道发育的整合模型。

An integrated model for intestinal development in the fetal sheep.

作者信息

Trahair J F, Robinson P M

机构信息

Department of Anatomy, University of Melbourne, Parkville, Victoria, Australia.

出版信息

Reprod Nutr Dev (1980). 1987;27(4):849-57. doi: 10.1051/rnd:19870611.

DOI:10.1051/rnd:19870611

PMID:3659566

Abstract

The interrelationships between 22 parameters relating to small intestinal morphology and enterocyte cell kinetics were investigated. It was found that all significant correlations could be related to changes in intestinal diameter. The area of accessory and mucosal coats in cross section was computed and a constancy of relative composition, independent of experimental perturbation, was noted. It appears likely that despite seemingly trophic responses in specific tissue components, an overall balance of these components is maintained in the developing intestine. The need to develop integrated models of gut structure and function to allow adequate interpretation of results is discussed.

摘要

研究了与小肠形态和肠上皮细胞动力学相关的22个参数之间的相互关系。发现所有显著的相关性都与肠直径的变化有关。计算了横截面中附属层和黏膜层的面积，并注意到相对组成的恒定性，不受实验干扰的影响。尽管特定组织成分中似乎有营养反应，但在发育中的肠道中这些成分的整体平衡似乎得以维持。讨论了开发肠道结构和功能综合模型以充分解释结果的必要性。