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斯普拉格-道利大鼠绒毛高度与营养状况之间的数学相关性。

Mathematical correlation between villus height and the nutritional state in Sprague-Dawley rats.

作者信息

Zambonino Infante J L, Rouanet J M, Besançon P

机构信息

Département Agroressources et Procédés Biologiques, Université de Montpellier II, France.

出版信息

Gut. 1993 Aug;34(8):1066-8. doi: 10.1136/gut.34.8.1066.

DOI:10.1136/gut.34.8.1066
PMID:8174955
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1374355/
Abstract

Three different experiments were carried out on growing male Sprague-Dawley rats. In the first experiment, dietary nitrogen was given in casein at four different protein values ranging from 5 to 16%. Rats were fed ad libitum for 21 days. In the second experiment, which lasted 17 days, animals were given three diets that differed in the molecular form of the nitrogen supply - that is, proteins or peptides. The protein value (N x 6.25) was 10% in each diet. In the third experiment, malnourished rats were refed diets with a protein value of 15% (N x 6.25) for eight days. The dietary nitrogen was either in the form of protein, peptide, or amino acid. Body weight was recorded daily. At the end of each experiment the intestinal villus height was measured by light microscopy. Data were statistically analysed by Exner's coefficient. The results assessed the validity of the correlation between villus height and gain in body weight.

摘要

对生长中的雄性斯普拉格-道利大鼠进行了三项不同的实验。在第一个实验中,以酪蛋白形式提供膳食氮,其蛋白质含量有四个不同水平,范围从5%到16%。大鼠自由采食21天。在持续17天的第二个实验中,给动物提供三种氮供应分子形式不同的饮食,即蛋白质或肽。每种饮食的蛋白质含量(氮×6.25)为10%。在第三个实验中,营养不良的大鼠重新喂食蛋白质含量为15%(氮×6.25)的饮食,持续八天。膳食氮的形式为蛋白质、肽或氨基酸。每天记录体重。在每个实验结束时,通过光学显微镜测量肠绒毛高度。数据采用埃克斯纳系数进行统计学分析。结果评估了绒毛高度与体重增加之间相关性的有效性。

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REACTION OF THE SMALL INTESTINE TO INDUCED PROTEIN MALNUTRITION IN RHESUS MONKEYS. A STUDY OF CELL POPULATION KINETICS IN THE JEJUNUM.恒河猴小肠对诱导性蛋白质营养不良的反应。空肠细胞群体动力学研究。
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