Luzhou Traditional Chinese Medicine Hospital Affiliated to Southwest Medical University, Luzhou, Sichuan, China.
Medicine (Baltimore). 2022 Dec 23;101(51):e32296. doi: 10.1097/MD.0000000000032296.
Lumbar disc herniation (LDH) is a common orthopedic disease, which is one of the main causes of global chronic pain and motor function defect. For intractable LDH, the surgical treatment of percutaneous transforaminal endoscopic discectomy (PTED) is often used in clinical practice. Although the operation is relatively mature, there may still be some limitations and surgical risks delaying the recovery process of patients. Some studies have found that the combination of acupuncture therapy and PTED can bring more benefits to patients, but these conclusions are still lack of evidence support. Therefore, this study will adopt the method of meta-analysis to estimate the effectiveness and safety of acupuncture combined with PTED in patients with LDH, in order to provide a basis for clinical decision-making.
This study will conduct a systematic search of the following databases: the Chinese databases China National Knowledge Infrastructure, formerly Chinese Biomedical Database, Wanfang Data, Chongqing VIP Database for Chinese Technical Periodicals, the PubMed, Medline, Embase, Web of Science and The Cochrane library, from their inception to December 1, 2022. In addition, we will search their references to avoid missing other eligible studies. The language will be limited to English and Chinese. RevMan 5.4 will be used to perform the meta-analysis. And GRADE Profiler software will be used to rate the quality of evidence.
The results will be submitted to a peer-reviewed journal.
This study can provide evidence support for acupuncture combined with PTED in the treatment of LDH.
腰椎间盘突出症（LDH）是一种常见的骨科疾病，是全球慢性疼痛和运动功能障碍的主要原因之一。对于难治性 LDH，临床实践中常采用经皮椎间孔内窥镜椎间盘切除术（PTED）进行手术治疗。虽然该手术相对成熟，但仍可能存在一些限制和手术风险，从而延迟患者的康复进程。一些研究发现，针灸疗法与 PTED 联合使用可以给患者带来更多益处，但这些结论仍缺乏证据支持。因此，本研究将采用荟萃分析的方法来评估针灸联合 PTED 治疗 LDH 患者的有效性和安全性，以期为临床决策提供依据。
本研究将对以下数据库进行系统检索：中国数据库中国知网、中国生物医学文献数据库、万方数据、重庆维普中文期刊数据库、PubMed、Medline、Embase、Web of Science 和 The Cochrane library，检索时间从建库至 2022 年 12 月 1 日。此外，还将检索其参考文献，以避免遗漏其他合格的研究。语言将限于英语和中文。使用 RevMan 5.4 进行荟萃分析。并使用 GRADE Profiler 软件对证据质量进行评级。
研究结果将提交给同行评议期刊。
本研究可为针灸联合 PTED 治疗 LDH 提供证据支持。
