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经皮椎间孔内镜椎间盘切除术与微创经皮内镜椎间盘切除术治疗症状性腰椎间盘突出症的比较:一项至少 2 年随访的多中心回顾性队列研究。

Comparison of Percutaneous Transforaminal Endoscopic Discectomy and Microendoscopic Discectomy for the Surgical Management of Symptomatic Lumbar Disc Herniation: A Multicenter Retrospective Cohort Study with a Minimum of 2 Years' Follow-Up.

机构信息

Department of Orthopedics, Beijing Tongren Hospital, Capital Medical University, Beijing, China.

Department of Orthopedics, Shanghai General Hospital affiliated to Jiaotong University, Shanghai, China.

出版信息

Pain Physician. 2021 Jan;24(1):E117-E125.

Abstract

BACKGROUND

Percutaneous transforaminal endoscopic discectomy (PTED) and microendoscopic discectomy (MED) are alternative minimally invasive procedures for the treatment of symptomatic lumbar disc herniation (LDH). However, insufficient literature exists to highlight the differences between the procedures.

OBJECTIVES

This study intended to clarify whether PTED results in better clinical outcomes compared with MED in the surgical management of single-level LDH.

STUDY DESIGN

A multicenter retrospective cohort study.

SETTING

This study took place in 2 spinal minimally invasive centers in Beijing, China.

METHODS

A multicenter retrospective study was conducted in consecutive patients diagnosed with symptomatic LDH receiving PTED or MED in 2 spinal minimally invasive centers from April 2009 to July 2016. A total of 1,053 patients were recruited, of which 632 underwent PTED and 421 underwent MED. All patients were followed with a minimum of 2 years; a set of clinical outcomes were extracted and analyzed.

RESULTS

The operation time was similar between groups (71.2 ± 15.1 minutes in the PTED group and 69.4 ± 12.5 minutes in the MED group; P = 0.518); length of incision was significantly shorter; intraoperative blood loss was less in the PTED group (P < 0.001); hospital stay was 3.6 ± 1.5 days in the PTED group and 5.4 ± 2.8 days in the MED group with significant differences detected (P = 0.018); however, intraoperative fluoroscopy was longer with significantly higher cost with the PTED group (P < 0.001). Transient dysesthesia and wound complications were more common in the MED group (P = 0.039 and P = 0.026, respectively); however, no significant differences were found with total complications (P = 0.139). Significant lower Visual Analog Scale pain score (back and leg) were detected on day 1 postoperatively (P = 0.007 and P = 0.018, respectively). No significant differences were found at all other time points (P > 0.05). Significantly better Oswestry Disability Index (ODI) score was detected postoperatively at 1 month in the PTED group (19.6 ± 9.8 vs. 27.2 ± 9.3; P = 0.016); ODI score at other time points did not differ significantly between groups (P > 0.05). Modified MacNab criteria showed that most patients experienced excellent and good results with no significant differences between groups (P = 0.511).

LIMITATION

This was a multicenter retrospective study wherein the surgeons may have introduced bias to the study.

CONCLUSIONS

Both PTED and MED present to be an acceptable long-term efficacy for the treatment of LDH. Although PTED is associated with longer intraoperative fluoroscopy and a little more cost, it should still be considered superior to MED considering the benefits of lesser invasion, shorter hospital stays, quicker pain relief, and functional recovery.

摘要

背景

经皮椎间孔内窥镜椎间盘切除术(PTED)和微创椎间盘切除术(MED)是治疗有症状腰椎间盘突出症(LDH)的两种替代微创手术。然而,目前还没有足够的文献来突出这两种手术之间的差异。

目的

本研究旨在明确在单节段 LDH 的手术治疗中,PTED 是否比 MED 能带来更好的临床结果。

研究设计

多中心回顾性队列研究。

地点

本研究在北京的 2 个脊柱微创中心进行。

方法

这是一项多中心回顾性研究,对 2009 年 4 月至 2016 年 7 月在 2 个脊柱微创中心接受 PTED 或 MED 治疗的有症状 LDH 患者进行了连续病例回顾。共纳入 1053 例患者,其中 632 例行 PTED,421 例行 MED。所有患者均随访至少 2 年;提取并分析了一组临床结果。

结果

两组的手术时间相似(PTED 组 71.2±15.1 分钟,MED 组 69.4±12.5 分钟;P=0.518);切口长度明显较短;PTED 组术中出血量较少(P<0.001);PTED 组的住院时间为 3.6±1.5 天,MED 组为 5.4±2.8 天,差异有统计学意义(P=0.018);然而,PTED 组术中透视时间更长,费用明显更高(P<0.001)。MED 组的短暂感觉异常和伤口并发症更为常见(P=0.039 和 P=0.026);然而,总并发症无显著差异(P=0.139)。术后第 1 天的视觉模拟评分(背部和腿部)显著降低(P=0.007 和 P=0.018)。在所有其他时间点,差异均无统计学意义(P>0.05)。术后 1 个月时,PTED 组的 Oswestry 残疾指数(ODI)评分显著更好(19.6±9.8 比 27.2±9.3;P=0.016);在其他时间点,两组的 ODI 评分无显著差异(P>0.05)。改良 MacNab 标准显示,两组患者大多获得了良好的治疗效果,差异无统计学意义(P=0.511)。

局限性

这是一项多中心回顾性研究,外科医生可能会对研究引入偏倚。

结论

PTED 和 MED 均为治疗 LDH 的长期有效方法。尽管 PTED 与术中透视时间较长和费用略高有关,但考虑到其微创、住院时间较短、疼痛缓解较快和功能恢复较好的优势,PTED 仍应优于 MED。

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