Faculty of Medicine, University of Novi Sad, Novi Sad, Serbia.
University Clinical Center of Vojvodina, Clinic for Obstetrics and Gynecology, Novi Sad, Serbia.
Medicine (Baltimore). 2022 Dec 30;101(52):e32552. doi: 10.1097/MD.0000000000032552.
Undifferentiated uterine sarcoma is a rare histological subtype of uterine sarcoma. This study aimed to summarize the clinical and pathological presentation of this case.
A 51-years-old patient was admitted to the clinic because of severe pain in the lower abdomen, and scanty bleeding from the genitals. Gynecological examination revealed an enlarged uterus. Conventional and Doppler transvaginal sonography detected a tumorously altered uterus with a maximum diameter of 20 cm a tumefaction with unclear borders and a diameter of 10 cm, with hyperechoic and hypoechoic fields within the tumefaction, presenting pathological vascularization and reduced values of the (Pulsatile index ≤ 1) and (Resistance index ≤ 0.40). Preoperatively, the chest, abdomen, and pelvis were examined. The patient underwent surgery and total abdominal hysterectomy with bilateral salpingo-oophorectomy, and partial omentectomy, with complete removal of the tumor. A pathohistological diagnosis, of undifferentiated uterine sarcoma, was made by excluding other types of uterine sarcomas. At the control examination after completion of chemotherapy, recurrence was ascertained.
undifferentiated uterine sarcoma is an aggressive malignant tumor that in most cases shows rapid progression of the disease after complete resection of the tumor, with a poor prognosis.
未分化子宫肉瘤是一种罕见的子宫肉瘤组织学亚型。本研究旨在总结该病例的临床和病理表现。
一名 51 岁患者因下腹剧烈疼痛和生殖器少量出血就诊。妇科检查发现子宫增大。常规和经阴道多普勒超声检查显示肿瘤性改变的子宫，最大直径为 20cm，有一个直径为 10cm 的肿块，边界不清，肿块内有高回声和低回声区，表现出病理性血管化和（脉动指数≤1）和（阻力指数≤0.40）值降低。术前检查了胸部、腹部和骨盆。患者接受了手术，行全子宫切除术和双侧输卵管卵巢切除术，以及部分网膜切除术，完全切除了肿瘤。通过排除其他类型的子宫肉瘤，做出了未分化子宫肉瘤的病理组织学诊断。在完成化疗后的随访检查中，发现了复发。
未分化子宫肉瘤是一种侵袭性恶性肿瘤，在大多数情况下，在肿瘤完全切除后，疾病迅速进展，预后不良。
