IRCCS Centro Neurolesi "Bonino Pulejo", Messina, Italy.
Medicine (Baltimore). 2022 Dec 30;101(52):e32526. doi: 10.1097/MD.0000000000032526.
The aim of this study is to verify the functional activation in a patient with anosognosia for hemiplegia following left brain lesions.
We report a case of a 53-year-old right-handed female patient. She came to our rehabilitative unit with a diagnosis of an ischemic major stroke in the left internal carotid artery and important hemiplegia to the right side. She underwent functional magnetic resonance imaging (fMRI), during which she performed a motor imagery task.
The fMRI assessment showed an ischemic lesion in the frontotemporal and insular left areas. In the fMRI experiment, we revealed activation of the residual neural patterns of both hemispheres.
We underlined an interest in the compensation mechanism that involved neural networks near brain lesions and some areas of the contro-lesional hemisphere, suggesting that the synaptic plasticity permitted an intra and inter-hemispheric reorganization of the cerebral system.
本研究旨在验证左脑病变后偏瘫失认症患者的功能激活情况。
我们报告了一例 53 岁的右利手女性患者。她因左侧颈内动脉的缺血性大中风和右侧严重偏瘫来到我们的康复病房。她接受了功能磁共振成像(fMRI)检查,在此期间她进行了一项运动想象任务。
fMRI 评估显示左额颞和岛叶区域存在缺血性病变。在 fMRI 实验中,我们揭示了两个半球残余神经模式的激活。
我们强调了一种补偿机制的兴趣,该机制涉及脑损伤附近的神经网络和对侧半球的一些区域,这表明突触可塑性允许大脑系统的内和半球间重组。