Department of Health Policy and Management, Keio University School of Medicine, Tokyo, Japan.
Department of Global Health Policy, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Ageing Res Rev. 2023 Mar;85:101839. doi: 10.1016/j.arr.2022.101839. Epub 2022 Dec 31.
We aimed to estimate the impact of social isolation on cognitive function and mental health among older adults during the two-year-and-a-half COVID-19 period. Pubmed Central, Medline, CINAHL Plus and PsychINFO were searched between March 1, 2020, and September 30, 2022. We included all studies that assessed proportions of older adults with the mean or the median with a minimum age above 60 reporting worsening cognitive function and mental health. Thirty-two studies from 18 countries met the eligibility criteria for meta-analyses. We found that the proportions of older adults with dementia who experienced worsening cognitive impairment and exacerbation or new onset of behavioral and psychological symptoms of dementia (BPSD) were approximately twice larger than that of older adults with HC experiencing SCD and worsening mental health. Stage of dementia, care options, and severity of mobility restriction measures did not yield significant differences in the number of older adults with dementia reporting worsening cognitive impairment and BPSD, while the length of isolation did for BPSD but not cognitive impairment. Our study highlights the impact of social isolation on cognitive function and mental health among older adults. Public health strategies should prioritize efforts to promote healthy lifestyles and proactive assessments.
我们旨在评估在 COVID-19 两年半期间，社会隔离对老年人认知功能和心理健康的影响。在 2020 年 3 月 1 日至 2022 年 9 月 30 日期间，我们检索了 PubMed Central、Medline、CINAHL Plus 和 PsychINFO。我们纳入了所有评估报告认知功能恶化和心理健康恶化的≥60 岁老年人比例的研究。来自 18 个国家的 32 项研究符合荟萃分析的纳入标准。我们发现，患有痴呆症的老年人中，认知障碍恶化和行为及心理症状的加重或新出现（BPSD）的比例大约是健康对照（HC）老年人中出现 SCD 和心理健康恶化的两倍。痴呆症的阶段、护理选择和移动受限措施的严重程度，对报告认知障碍恶化和 BPSD 的痴呆症老年人数量没有显著差异，而隔离时间长短对 BPSD 有影响，但对认知障碍没有影响。我们的研究强调了社会隔离对老年人认知功能和心理健康的影响。公共卫生策略应优先重视促进健康生活方式和主动评估。
