Louisiana State University Health Science Centre, Shreveport, Louisiana, USA.
Department of Medicine, Section of Endocrine, Aga Khan University Hospital, Karachi, Pakistan.
J Coll Physicians Surg Pak. 2022 Dec;32(12):SS162-SS164. doi: 10.29271/jcpsp.2022.Supp0.SS162.
Diabetic myonecrosis is an unpublicised problem that can occur in patients having either type 1 or type 2 diabetes mellitus. It usually affects patients who have long-standing, uncontrolled diabetes with associated microvascular complications. We report a case of a 78-year female with diabetic myonecroses admitted to a tertiary care hospital. Although it is a self-limiting disease, we lay down the management approach of how to exclude the extensive list of differential diagnoses and limit the life-threatening complications as urgent evaluation is critical. Clinicians taking care of patients with uncontrolled diabetes should be mindful and aware of the complication of diabetic myonecrosis in a patient presenting with pain in any limb and having negative venous doppler ultrasound for deep vein thrombosis. Magnetic resonance imaging (MRI) is the most specific and sensitive modality for diagnosis. Muscle biopsy can be used for anomalous cases. Although diabetic muscle infarction is a rare pathology, it presents a high risk for diabetes-related morbidity and mortality. Key Words: Myonecrosis, Diabetes mellitus, Doppler ultrasound, Magnetic resonance imaging.
糖尿病性肌坏死是一种未被公开报道的问题，可发生于 1 型或 2 型糖尿病患者中。它通常影响长期、未得到控制的糖尿病伴有微血管并发症的患者。我们报告了一例 78 岁女性糖尿病性肌坏死患者，该患者入住一家三级保健医院。虽然它是一种自限性疾病，但我们阐述了如何排除广泛的鉴别诊断列表并限制危及生命的并发症的管理方法，因为紧急评估至关重要。照顾未控制糖尿病患者的临床医生应该注意并意识到在任何肢体出现疼痛且下肢静脉多普勒超声检查无深静脉血栓形成的情况下，糖尿病性肌坏死的并发症。磁共振成像（MRI）是诊断最特异和敏感的方式。肌肉活检可用于异常情况。尽管糖尿病性肌梗死是一种罕见的病理学，但它会增加与糖尿病相关的发病率和死亡率的风险。关键词：肌坏死、糖尿病、多普勒超声、磁共振成像。
