Pulmonary, Allergy, Sleep and Critical Care Medicine Section, Veterans Affairs Boston Healthcare System; Harvard Medical School and Brigham and Women's, Boston, Massachusetts.
San Francisco VA Medical Center, UC San Francisco School of Medicine, San Francisco; Division of Occupational and Environmental Medicine, Department of Medicine, University of California San Francisco, California, USA.
Curr Opin Pulm Med. 2023 Mar 1;29(2):83-89. doi: 10.1097/MCP.0000000000000946. Epub 2023 Jan 4.
Military personnel deployed to Southwest Asia and Afghanistan were potentially exposed to high levels of fine particulate matter and other pollutants from multiple sources, including dust storms, burn pit emissions from open-air waste burning, local ambient air pollution, and a range of military service-related activities that can generate airborne exposures. These exposures, individually or in combination, can have adverse respiratory health effects. We review exposures and potential health impacts, providing a framework for evaluation.
Particulate matter exposures during deployment exceeded U.S. National Ambient Air Quality Standards. Epidemiologic studies and case series suggest that in postdeployment Veterans with respiratory symptoms, asthma is the most commonly diagnosed illness. Small airway abnormalities, most notably particularly constrictive bronchiolitis, have been reported in a small number of deployers, but many are left without an established diagnosis for their respiratory symptoms. The Promise to Address Comprehensive Toxics Act was enacted to provide care for conditions presumed to be related to deployment exposures. Rigorous study of long-term postdeployment health has been limited.
Veterans postdeployment to Southwest Asia and Afghanistan with respiratory symptoms should undergo an exposure assessment and comprehensive medical evaluation. If required, more advanced diagnostic considerations should be utilized in a setting that can provide multidisciplinary expertise and long-term follow-up.
目的综述:部署到西南亚和阿富汗的军人可能会接触到来自多个来源的高浓度细颗粒物和其他污染物,包括沙尘暴、露天焚烧废物排放的燃烧坑排放物、当地环境空气污染以及一系列可能产生空气传播暴露的军事相关活动。这些暴露单独或组合在一起,可能会对呼吸道健康产生不良影响。我们回顾了暴露情况和潜在的健康影响,为评估提供了框架。
最新发现:部署期间的颗粒物暴露量超过了美国国家环境空气质量标准。流行病学研究和病例系列表明,在有呼吸道症状的退伍军人中,哮喘是最常见的诊断疾病。在少数部署者中报告了小气道异常,尤其是特发性缩窄性细支气管炎,但许多人仍未确定其呼吸道症状的明确诊断。《全面有毒物质应对承诺法案》的颁布是为了为那些被认为与部署暴露有关的疾病提供治疗。对长期部署后健康状况的严格研究受到限制。
总结:部署到西南亚和阿富汗后出现呼吸道症状的退伍军人应进行暴露评估和全面的医学评估。如果需要,应在能够提供多学科专业知识和长期随访的环境中利用更先进的诊断考虑因素。